TY - JOUR
T1 - Current Role of Myocardial Viability Imaging Using Positron Emission Tomography in Patients with Chronic Ischemic Heart Failure and Left Ventricular Dysfunction
AU - Kjærulff, Mette Louise Gram
AU - Madsen, Simon
AU - Luong, Thien Vinh
AU - Pryds, Kasper
AU - Nielsen, Roni
AU - Gormsen, Lars Christian
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2023/10
Y1 - 2023/10
N2 - Purpose of Review: It is currently debated what role cardiac viability imaging plays in clinical practice, as newer randomized studies have refuted the previously reported beneficial effects of non-invasive imaging-guided decision-making for revascularization. This review provides an overview of previous literature and recent findings on the clinical use of viability PET imaging in revascularization decision-making for patients with chronic ischemic heart failure. Recent Findings: Recent studies have concluded that preoperative myocardial viability assessment by PET imaging does not have significant predictive value for outcomes following revascularization in patients with ischemic heart failure. Alternative PET metrics, e.g., myocardial flow reserve obtained through a less time-consuming protocol compared to FDG PET, have the potential to predict revascularization outcomes. Summary: Viability assessment prior to revascularization may not be as significant in clinical practice as it was previously thought. This shift in perspective is likely due to the retrospective nature of earlier studies, coupled with the progress made in heart failure treatment.
AB - Purpose of Review: It is currently debated what role cardiac viability imaging plays in clinical practice, as newer randomized studies have refuted the previously reported beneficial effects of non-invasive imaging-guided decision-making for revascularization. This review provides an overview of previous literature and recent findings on the clinical use of viability PET imaging in revascularization decision-making for patients with chronic ischemic heart failure. Recent Findings: Recent studies have concluded that preoperative myocardial viability assessment by PET imaging does not have significant predictive value for outcomes following revascularization in patients with ischemic heart failure. Alternative PET metrics, e.g., myocardial flow reserve obtained through a less time-consuming protocol compared to FDG PET, have the potential to predict revascularization outcomes. Summary: Viability assessment prior to revascularization may not be as significant in clinical practice as it was previously thought. This shift in perspective is likely due to the retrospective nature of earlier studies, coupled with the progress made in heart failure treatment.
KW - Coronary artery disease
KW - Coronary revascularization
KW - Ischemic heart failure
KW - Myocardial viability
KW - Nuclear cardiology
KW - Positron emission tomography
UR - http://www.scopus.com/inward/record.url?scp=85169164098&partnerID=8YFLogxK
U2 - 10.1007/s12410-023-09582-4
DO - 10.1007/s12410-023-09582-4
M3 - Review
AN - SCOPUS:85169164098
SN - 1941-9066
VL - 16
SP - 83
EP - 92
JO - Current cardiovascular imaging reports
JF - Current cardiovascular imaging reports
IS - 10
ER -