Abstract
Fractional flow reserve (FFR) measured during invasive coronary angiography is an independent prognosticator in patients with coronary artery disease and the gold standard for decision making in coronary revascularization. The integration of computational fluid dynamics and quantitative anatomic and physiologic modeling now enables simulation of patient-specific hemodynamic parameters including blood velocity, pressure, pressure gradients, and FFR from standard acquired coronary computed tomography (CT) datasets. In this review article, we describe the potential impact on clinical practice and the science behind noninvasive coronary computed tomography (CT) angiography derived fractional flow reserve (FFRCT) as well as future applications of this technology in treatment planning and quantifying forces on atherosclerotic plaques.
| Original language | English |
|---|---|
| Article number | 2 |
| Journal | Current cardiovascular imaging reports |
| Volume | 9 |
| Issue | 1 |
| Pages (from-to) | 2 |
| Number of pages | 12 |
| ISSN | 1941-9066 |
| DOIs | |
| Publication status | Published - 5 Mar 2016 |
Keywords
- Atherosclerosis
- Axial plaque stress
- Computational fluid dynamics
- Coronary artery disease
- Coronary computed tomography angiography
- Coronary plaque
- Fractional flow reserve
- Invasive coronary angiography
- Myocardial ischemia
- Noninvasive cardiac imaging
- Noninvasive diagnostic testing
- Prognosis
- Wall shear stress