Continuous Theta Burst Stimulation to the left anterior medial prefrontal cortex influences metacognitive efficiency

Justyna Hobot*, Zuzanna Skóra, Michał Wierzchoń, Kristian Sandberg

*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Abstract

The contribution of the prefrontal areas to visual awareness is critical for the Global Neuronal Workspace Theory and higher-order theories of consciousness. The goal of the present study was to test the potential engagement of the anterior medial prefrontal cortex (aMPFC) in visual awareness judgements. We aimed to temporarily influence the neuronal dynamics of the left aMPFC via neuroplasticity-like mechanisms. We used different Theta Burst Stimulation (TBS) protocols in combination with a visual identification task and visual awareness ratings. Either continuous TBS (cTBS), intermittent TBS (iTBS), or sham TBS was applied prior to the experimental paradigm in a within-participant design. Compared with sham TBS, we observed an increase in participants’ ability to judge their perception adequately (metacognitive efficiency) following cTBS but not iTBS. The effect was accompanied by lower visual awareness ratings in incorrect responses. No significant differences in the identification task performance were observed. We interpret these results as evidence of the involvement of PFC in the brain network that underlies metacognition. Further, we discuss whether the results of TMS studies on perceptual metacognition can be taken as evidence for PFC involvement in awareness itself.

Original languageEnglish
Article number119991
JournalNeuroImage
Volume272
Number of pages13
ISSN1053-8119
DOIs
Publication statusPublished - May 2023

Keywords

  • Anterior prefrontal cortex
  • Identification task
  • Metacognition
  • Subjective ratings
  • Theta burst stimulation
  • Visual awareness

Fingerprint

Dive into the research topics of 'Continuous Theta Burst Stimulation to the left anterior medial prefrontal cortex influences metacognitive efficiency'. Together they form a unique fingerprint.

Cite this