Clove oil nanoemulsion as an effective antibacterial agent: Taguchi optimization method

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  • Mohammad Hassan Shahavi, Babol University of Technology
  • ,
  • Morteza Hosseini, Babol University of Technology
  • ,
  • Mohsen Jahanshahi, Babol University of Technology
  • ,
  • Rikke Louise Meyer
  • Ghasem Najafpour Darzi, Babol University of Technology

Clove oil is an essential oil used as a biodegradable antibacterial agent in food and pharmaceutical products. Emulsions are used to stabilize and increase the antimicrobial efficacy of oils in aqueous solutions. Smaller droplets provide better distribution of the oil. In this study, we formulate clove oil in aqueous solution by nanoemulsion. The aim of this study was to optimize key parameters in the preparation of clove oil nanoemulsion to obtain stable emulsions with less than 50 nm droplet size. The evaluated parameters include the concentration of clove oil, concentration of emulsifier, hydrophilic–lipophilic balance (HLB) number, and ultrasonication time. We determined the following response parameters: droplet size, polydispersity index, and zeta potential, and we aimed to achieve

Original languageEnglish
JournalDesalination and Water Treatment
Pages (from-to)18379-18390
Publication statusPublished - Aug 2016

    Research areas

  • Antibacterial, Clove oil, Droplet size, Nanoemulsion, Taguchi optimization

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