Clinical presentation and microbiology of acute salivary gland infections

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Clinical presentation and microbiology of acute salivary gland infections. / Danstrup, Christian Sander; Münch, Henrik Jonathan; Klug, Tejs Ehlers; Fuursted, Kurt; Ovesen, Therese.

In: Danish Medical Journal, Vol. 67, No. 6, A11190659, 2020.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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APA

CBE

Danstrup CS, Münch HJ, Klug TE, Fuursted K, Ovesen T. 2020. Clinical presentation and microbiology of acute salivary gland infections. Danish Medical Journal. 67(6):Article A11190659.

MLA

Danstrup, Christian Sander et al. "Clinical presentation and microbiology of acute salivary gland infections". Danish Medical Journal. 2020. 67(6).

Vancouver

Danstrup CS, Münch HJ, Klug TE, Fuursted K, Ovesen T. Clinical presentation and microbiology of acute salivary gland infections. Danish Medical Journal. 2020;67(6). A11190659.

Author

Danstrup, Christian Sander ; Münch, Henrik Jonathan ; Klug, Tejs Ehlers ; Fuursted, Kurt ; Ovesen, Therese. / Clinical presentation and microbiology of acute salivary gland infections. In: Danish Medical Journal. 2020 ; Vol. 67, No. 6.

Bibtex

@article{1e311ebdaef74f988d37963d3cabc6cc,
title = "Clinical presentation and microbiology of acute salivary gland infections",
abstract = "INTRODUCTION: Acute salivary gland infections (ASI) have been associated with poor outcome in elderly and postoperative patients. Perioperative care and treatment of co-morbidities have improved considerably, but most of our knowledge regarding ASI dates back several decades. The aim of this study was to describe the microbiology and treatment of ASI in a large post-millennial cohort. METHODS: All patients with ASI admitted to the Department of Otorhinolaryngology – Head and Neck Surgery, Aarhus University Hospital in the period from 2001 to 2017 were included. RESULTS: In total, 157 patients with ASI were included. The parotid gland (PG) was affected in 89 (57%) cases and the submandibular gland (SMG) in 68 (43%) cases. The most prevalent bacterial findings were viridans streptococci (25 isolates) and Staphylococcus aureus (19 isolates). S. aureus was almost exclusively found in PG (17/19 cases). S. aureus-positive cases showed a significantly higher inflammatory response than other bacteria (C-reactive protein, p = 0.008 and absolute neutrophil count, p = 0.0108). CONCLUSIONS: S. aureus is a significant pathogen in ASI and especially in PG cases. Other pathogens may play a role in the development of SMG infections. Based on the bacterial findings in this study, we recommend penicillinase-resistant penicillin as first-line treatment in ASI.",
author = "Danstrup, {Christian Sander} and M{\"u}nch, {Henrik Jonathan} and Klug, {Tejs Ehlers} and Kurt Fuursted and Therese Ovesen",
year = "2020",
language = "English",
volume = "67",
journal = "Danish Medical Journal",
issn = "2245-1919",
publisher = "Den Almindelige Danske L{\ae}geforening",
number = "6",

}

RIS

TY - JOUR

T1 - Clinical presentation and microbiology of acute salivary gland infections

AU - Danstrup, Christian Sander

AU - Münch, Henrik Jonathan

AU - Klug, Tejs Ehlers

AU - Fuursted, Kurt

AU - Ovesen, Therese

PY - 2020

Y1 - 2020

N2 - INTRODUCTION: Acute salivary gland infections (ASI) have been associated with poor outcome in elderly and postoperative patients. Perioperative care and treatment of co-morbidities have improved considerably, but most of our knowledge regarding ASI dates back several decades. The aim of this study was to describe the microbiology and treatment of ASI in a large post-millennial cohort. METHODS: All patients with ASI admitted to the Department of Otorhinolaryngology – Head and Neck Surgery, Aarhus University Hospital in the period from 2001 to 2017 were included. RESULTS: In total, 157 patients with ASI were included. The parotid gland (PG) was affected in 89 (57%) cases and the submandibular gland (SMG) in 68 (43%) cases. The most prevalent bacterial findings were viridans streptococci (25 isolates) and Staphylococcus aureus (19 isolates). S. aureus was almost exclusively found in PG (17/19 cases). S. aureus-positive cases showed a significantly higher inflammatory response than other bacteria (C-reactive protein, p = 0.008 and absolute neutrophil count, p = 0.0108). CONCLUSIONS: S. aureus is a significant pathogen in ASI and especially in PG cases. Other pathogens may play a role in the development of SMG infections. Based on the bacterial findings in this study, we recommend penicillinase-resistant penicillin as first-line treatment in ASI.

AB - INTRODUCTION: Acute salivary gland infections (ASI) have been associated with poor outcome in elderly and postoperative patients. Perioperative care and treatment of co-morbidities have improved considerably, but most of our knowledge regarding ASI dates back several decades. The aim of this study was to describe the microbiology and treatment of ASI in a large post-millennial cohort. METHODS: All patients with ASI admitted to the Department of Otorhinolaryngology – Head and Neck Surgery, Aarhus University Hospital in the period from 2001 to 2017 were included. RESULTS: In total, 157 patients with ASI were included. The parotid gland (PG) was affected in 89 (57%) cases and the submandibular gland (SMG) in 68 (43%) cases. The most prevalent bacterial findings were viridans streptococci (25 isolates) and Staphylococcus aureus (19 isolates). S. aureus was almost exclusively found in PG (17/19 cases). S. aureus-positive cases showed a significantly higher inflammatory response than other bacteria (C-reactive protein, p = 0.008 and absolute neutrophil count, p = 0.0108). CONCLUSIONS: S. aureus is a significant pathogen in ASI and especially in PG cases. Other pathogens may play a role in the development of SMG infections. Based on the bacterial findings in this study, we recommend penicillinase-resistant penicillin as first-line treatment in ASI.

UR - http://www.scopus.com/inward/record.url?scp=85087096582&partnerID=8YFLogxK

M3 - Journal article

AN - SCOPUS:85087096582

VL - 67

JO - Danish Medical Journal

JF - Danish Medical Journal

SN - 2245-1919

IS - 6

M1 - A11190659

ER -