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Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition

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DOI

  • Longguang Jiang, Fuzhou University
    • ,
  • Emil Oldenburg
  • Tobias Kromann-Hansen
    • ,
  • Peng Xu, Chinese Academy of Sciences
    • ,
  • Jan K. Jensen
  • Peter A. Andreasen
    • ,
  • Mingdong Huang, Fuzhou University, Chinese Academy of Sciences
Original languageEnglish
JournalBiochimica et Biophysica Acta - General Subjects
Volume1862
Issue9
Pages (from-to)2017-2023
Number of pages7
ISSN0304-4165
DOIs
Publication statusPublished - Sep 2018

    Research areas

  • Crystal structure, Cyclic peptide, Enzyme catalysis, Protease inhibitor, Substrate

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