Ciprofloxacin resistance in bacteria from a wastewater treatment plant: Combining genomics and metabolomics to identify Ciprofloxacin-tolerant strains by 16S amplicon sequencing

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@conference{9774e66e7ac247d18a01c4c38bfe194a,
title = "Ciprofloxacin resistance in bacteria from a wastewater treatment plant: Combining genomics and metabolomics to identify Ciprofloxacin-tolerant strains by 16S amplicon sequencing",
abstract = "Ciprofloxacin, a fluoroquinolone-type broad spectrum antibiotic, was found to persist through wastewater treatment. This raises questions on how an antibiotic affects the native microbial community of wastewater treatment plants, and if this – in addition to hampering treatment – inadvertently contributes to antibiotic resistance; a continuing, severe challenge to medical procedures and treatment. We investigated isolates from the activated sludge communities in a Danish wastewater treatment plant to determine any ciprofloxacin-tolerant species, and discovered a number of strains able to grow when exposed to various concentrations of the drug.",
keywords = "Resistens, DNA/analysis, GENOMICS, spildevand, spildevandsteknologier, Antibiotic resistance",
author = "Aggerbeck, {Marie R{\o}nne} and Martin Hansen and Anders Johansen and Alex Gobbi and Lea Ellegaard-Jensen and Hansen, {Lars Hestbjerg}",
year = "2019",
month = nov,
day = "19",
language = "English",

}

RIS

TY - CONF

T1 - Ciprofloxacin resistance in bacteria from a wastewater treatment plant

T2 - Combining genomics and metabolomics to identify Ciprofloxacin-tolerant strains by 16S amplicon sequencing

AU - Aggerbeck, Marie Rønne

AU - Hansen, Martin

AU - Johansen, Anders

AU - Gobbi, Alex

AU - Ellegaard-Jensen, Lea

AU - Hansen, Lars Hestbjerg

PY - 2019/11/19

Y1 - 2019/11/19

N2 - Ciprofloxacin, a fluoroquinolone-type broad spectrum antibiotic, was found to persist through wastewater treatment. This raises questions on how an antibiotic affects the native microbial community of wastewater treatment plants, and if this – in addition to hampering treatment – inadvertently contributes to antibiotic resistance; a continuing, severe challenge to medical procedures and treatment. We investigated isolates from the activated sludge communities in a Danish wastewater treatment plant to determine any ciprofloxacin-tolerant species, and discovered a number of strains able to grow when exposed to various concentrations of the drug.

AB - Ciprofloxacin, a fluoroquinolone-type broad spectrum antibiotic, was found to persist through wastewater treatment. This raises questions on how an antibiotic affects the native microbial community of wastewater treatment plants, and if this – in addition to hampering treatment – inadvertently contributes to antibiotic resistance; a continuing, severe challenge to medical procedures and treatment. We investigated isolates from the activated sludge communities in a Danish wastewater treatment plant to determine any ciprofloxacin-tolerant species, and discovered a number of strains able to grow when exposed to various concentrations of the drug.

KW - Resistens

KW - DNA/analysis

KW - GENOMICS

KW - spildevand

KW - spildevandsteknologier

KW - Antibiotic resistance

M3 - Poster

ER -