Ciprofloxacin resistance in bacteria from a wastewater treatment plant: Combining genomics and metabolomics to identify Ciprofloxacin-tolerant strains by 16S amplicon sequencing

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Ciprofloxacin, a fluoroquinolone-type broad spectrum antibiotic, was found to persist through wastewater treatment. This raises questions on how an antibiotic affects the native microbial community of wastewater treatment plants, and if this – in addition to hampering treatment – inadvertently contributes to antibiotic resistance; a continuing, severe challenge to medical procedures and treatment. We investigated isolates from the activated sludge communities in a Danish wastewater treatment plant to determine any ciprofloxacin-tolerant species, and discovered a number of strains able to grow when exposed to various concentrations of the drug.
Original languageEnglish
Publication year19 Nov 2019
Number of pages1
Publication statusPublished - 19 Nov 2019

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