Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer

Karsten Zieger; Carsten Wiuf; Klaus Møller-Ernst Jensen; Torben Falck Ørntoft; Lars Dyrskjøt Andersen

doi:10.1186/1471-2407-9-149

Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer

Karsten Zieger, Carsten Wiuf, Klaus Møller-Ernst Jensen, Torben Falck Ørntoft, Lars Dyrskjøt Andersen

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

13 Citations (Scopus)

Abstract

Non-muscle invasive bladder neoplasms with invasion of the lamina propria (stage T1) or high grade of dysplasia are at "high risk" of progression to life-threatening cancer. However, the individual course is difficult to predict. Chromosomal instability (CI) is associated with high tumor stage and grade, and possibly with the risk of progression.

Original language	English
Journal	B M C Cancer
Volume	9
Pages (from-to)	149
ISSN	1471-2407
DOIs	https://doi.org/10.1186/1471-2407-9-149
Publication status	Published - 1 Jan 2009

Keywords

Aged
Aged, 80 and over
Case-Control Studies
Chromosome Aberrations
Disease Progression
Female
Gene Dosage
Genome, Human
Humans
Loss of Heterozygosity
Male
Middle Aged
Neoplasm Staging
Polymerase Chain Reaction
Polymorphism, Single Nucleotide
Urinary Bladder Neoplasms

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10.1186/1471-2407-9-149

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title = "Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer",

abstract = "Non-muscle invasive bladder neoplasms with invasion of the lamina propria (stage T1) or high grade of dysplasia are at {"}high risk{"} of progression to life-threatening cancer. However, the individual course is difficult to predict. Chromosomal instability (CI) is associated with high tumor stage and grade, and possibly with the risk of progression.",

keywords = "Aged, Aged, 80 and over, Case-Control Studies, Chromosome Aberrations, Disease Progression, Female, Gene Dosage, Genome, Human, Humans, Loss of Heterozygosity, Male, Middle Aged, Neoplasm Staging, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Urinary Bladder Neoplasms",

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doi = "10.1186/1471-2407-9-149",

language = "English",

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TY - JOUR

T1 - Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer

AU - Zieger, Karsten

AU - Wiuf, Carsten

AU - Jensen, Klaus Møller-Ernst

AU - Ørntoft, Torben Falck

AU - Andersen, Lars Dyrskjøt

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Non-muscle invasive bladder neoplasms with invasion of the lamina propria (stage T1) or high grade of dysplasia are at "high risk" of progression to life-threatening cancer. However, the individual course is difficult to predict. Chromosomal instability (CI) is associated with high tumor stage and grade, and possibly with the risk of progression.

AB - Non-muscle invasive bladder neoplasms with invasion of the lamina propria (stage T1) or high grade of dysplasia are at "high risk" of progression to life-threatening cancer. However, the individual course is difficult to predict. Chromosomal instability (CI) is associated with high tumor stage and grade, and possibly with the risk of progression.

KW - Aged

KW - Aged, 80 and over

KW - Case-Control Studies

KW - Chromosome Aberrations

KW - Disease Progression

KW - Female

KW - Gene Dosage

KW - Genome, Human

KW - Humans

KW - Loss of Heterozygosity

KW - Male

KW - Middle Aged

KW - Neoplasm Staging

KW - Polymerase Chain Reaction

KW - Polymorphism, Single Nucleotide

KW - Urinary Bladder Neoplasms

U2 - 10.1186/1471-2407-9-149

DO - 10.1186/1471-2407-9-149

M3 - Journal article

C2 - 19445696

SN - 1471-2407

VL - 9

SP - 149

JO - B M C Cancer

JF - B M C Cancer

ER -

Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer

Abstract

Keywords

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