Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

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Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases. / Fugger, Lars; Jensen, Lise Torp; Rossjohn, Jamie.

In: Cell, Vol. 181, No. 1, 04.2020, p. 63-80.

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@article{3942a635943d411f9038975421e08d11,
title = "Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases",
abstract = "Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.",
author = "Lars Fugger and Jensen, {Lise Torp} and Jamie Rossjohn",
year = "2020",
month = apr,
doi = "10.1016/j.cell.2020.03.007",
language = "English",
volume = "181",
pages = "63--80",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "1",

}

RIS

TY - JOUR

T1 - Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

AU - Fugger, Lars

AU - Jensen, Lise Torp

AU - Rossjohn, Jamie

PY - 2020/4

Y1 - 2020/4

N2 - Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.

AB - Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.

UR - http://www.scopus.com/inward/record.url?scp=85082423259&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.03.007

DO - 10.1016/j.cell.2020.03.007

M3 - Review

C2 - 32243797

AN - SCOPUS:85082423259

VL - 181

SP - 63

EP - 80

JO - Cell

JF - Cell

SN - 0092-8674

IS - 1

ER -