Department of Economics and Business Economics

Cause-specific life years lost among persons diagnosed with schizophrenia: Is it getting better or worse?

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Cause-specific life years lost among persons diagnosed with schizophrenia : Is it getting better or worse? / Laursen, Thomas Munk; Plana-Ripoll, Oleguer; Andersen, Per Kragh; McGrath, John J; Tønder Nielsen, Anita; Nordentoft, Merete; Canudas-Romo, Vladimir; Erlangsen, Annette.

In: Schizophrenia Research, Vol. 206, 04.2019, p. 284-290.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Laursen, TM, Plana-Ripoll, O, Andersen, PK, McGrath, JJ, Tønder Nielsen, A, Nordentoft, M, Canudas-Romo, V & Erlangsen, A 2019, 'Cause-specific life years lost among persons diagnosed with schizophrenia: Is it getting better or worse?', Schizophrenia Research, vol. 206, pp. 284-290. https://doi.org/10.1016/j.schres.2018.11.003

APA

Laursen, T. M., Plana-Ripoll, O., Andersen, P. K., McGrath, J. J., Tønder Nielsen, A., Nordentoft, M., Canudas-Romo, V., & Erlangsen, A. (2019). Cause-specific life years lost among persons diagnosed with schizophrenia: Is it getting better or worse? Schizophrenia Research, 206, 284-290. https://doi.org/10.1016/j.schres.2018.11.003

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MLA

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Author

Laursen, Thomas Munk ; Plana-Ripoll, Oleguer ; Andersen, Per Kragh ; McGrath, John J ; Tønder Nielsen, Anita ; Nordentoft, Merete ; Canudas-Romo, Vladimir ; Erlangsen, Annette. / Cause-specific life years lost among persons diagnosed with schizophrenia : Is it getting better or worse?. In: Schizophrenia Research. 2019 ; Vol. 206. pp. 284-290.

Bibtex

@article{ec0c542cf37949feb3cab8fbbd1b362d,
title = "Cause-specific life years lost among persons diagnosed with schizophrenia: Is it getting better or worse?",
abstract = "BACKGROUND: People with schizophrenia have an increased risk of premature mortality compared to the general population. We aimed to quantify which types of causes of death contributed to the excess mortality, and to examine whether there has been an increase in the excess mortality among persons with schizophrenia in the period 1995 to 2015.METHOD: We used a cohort design including the entire Danish population. We calculated life years lost of the cohort members compared to a set reference-age at 95 years old. Using a decomposition model we examined differences of cause-specific death among those with schizophrenia and the general population, including calendar trends during the last two decades.RESULTS: In the general population, as well as in persons with schizophrenia, we found improvements in life years lost during the last two decades. Men with schizophrenia lost 13.5 years more than the general population (women; 11.4 years). Compared to the general population, a large improvement in life years lost with respect to suicide and accidents was found in those with schizophrenia, but, this improvement was offset by an increasing number of life years lost in deaths from diseases and medical conditions.CONCLUSION: Our findings highlight the urgent need for focused treatment of general medical conditions in those with schizophrenia. Without such an investment, it is probable that the life years lost among persons with schizophrenia (compared to the general population) will continue to worsen in future decades.",
keywords = "Calendar-trend, Life years lost, Mortality, Schizophrenia, REGISTER, ILLNESS, DEATH, EXPECTANCY, EXCESS MORTALITY, MENTAL-DISORDERS, GAP, life years lost, COHORT, PEOPLE, SUICIDE",
author = "Laursen, {Thomas Munk} and Oleguer Plana-Ripoll and Andersen, {Per Kragh} and McGrath, {John J} and {T{\o}nder Nielsen}, Anita and Merete Nordentoft and Vladimir Canudas-Romo and Annette Erlangsen",
note = "Copyright {\textcopyright} 2018 Elsevier B.V. All rights reserved.",
year = "2019",
month = apr,
doi = "10.1016/j.schres.2018.11.003",
language = "English",
volume = "206",
pages = "284--290",
journal = "Schizophrenia Research",
issn = "0920-9964",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Cause-specific life years lost among persons diagnosed with schizophrenia

T2 - Is it getting better or worse?

AU - Laursen, Thomas Munk

AU - Plana-Ripoll, Oleguer

AU - Andersen, Per Kragh

AU - McGrath, John J

AU - Tønder Nielsen, Anita

AU - Nordentoft, Merete

AU - Canudas-Romo, Vladimir

AU - Erlangsen, Annette

N1 - Copyright © 2018 Elsevier B.V. All rights reserved.

PY - 2019/4

Y1 - 2019/4

N2 - BACKGROUND: People with schizophrenia have an increased risk of premature mortality compared to the general population. We aimed to quantify which types of causes of death contributed to the excess mortality, and to examine whether there has been an increase in the excess mortality among persons with schizophrenia in the period 1995 to 2015.METHOD: We used a cohort design including the entire Danish population. We calculated life years lost of the cohort members compared to a set reference-age at 95 years old. Using a decomposition model we examined differences of cause-specific death among those with schizophrenia and the general population, including calendar trends during the last two decades.RESULTS: In the general population, as well as in persons with schizophrenia, we found improvements in life years lost during the last two decades. Men with schizophrenia lost 13.5 years more than the general population (women; 11.4 years). Compared to the general population, a large improvement in life years lost with respect to suicide and accidents was found in those with schizophrenia, but, this improvement was offset by an increasing number of life years lost in deaths from diseases and medical conditions.CONCLUSION: Our findings highlight the urgent need for focused treatment of general medical conditions in those with schizophrenia. Without such an investment, it is probable that the life years lost among persons with schizophrenia (compared to the general population) will continue to worsen in future decades.

AB - BACKGROUND: People with schizophrenia have an increased risk of premature mortality compared to the general population. We aimed to quantify which types of causes of death contributed to the excess mortality, and to examine whether there has been an increase in the excess mortality among persons with schizophrenia in the period 1995 to 2015.METHOD: We used a cohort design including the entire Danish population. We calculated life years lost of the cohort members compared to a set reference-age at 95 years old. Using a decomposition model we examined differences of cause-specific death among those with schizophrenia and the general population, including calendar trends during the last two decades.RESULTS: In the general population, as well as in persons with schizophrenia, we found improvements in life years lost during the last two decades. Men with schizophrenia lost 13.5 years more than the general population (women; 11.4 years). Compared to the general population, a large improvement in life years lost with respect to suicide and accidents was found in those with schizophrenia, but, this improvement was offset by an increasing number of life years lost in deaths from diseases and medical conditions.CONCLUSION: Our findings highlight the urgent need for focused treatment of general medical conditions in those with schizophrenia. Without such an investment, it is probable that the life years lost among persons with schizophrenia (compared to the general population) will continue to worsen in future decades.

KW - Calendar-trend

KW - Life years lost

KW - Mortality

KW - Schizophrenia

KW - REGISTER

KW - ILLNESS

KW - DEATH

KW - EXPECTANCY

KW - EXCESS MORTALITY

KW - MENTAL-DISORDERS

KW - GAP

KW - life years lost

KW - COHORT

KW - PEOPLE

KW - SUICIDE

U2 - 10.1016/j.schres.2018.11.003

DO - 10.1016/j.schres.2018.11.003

M3 - Journal article

C2 - 30446270

VL - 206

SP - 284

EP - 290

JO - Schizophrenia Research

JF - Schizophrenia Research

SN - 0920-9964

ER -