Case of primary low-grade neuroendocrine carcinoma of the skin

Sara Krogh; Mette Bak Nielsen; Linda Skibsted Kornerup; Gitte Dam

doi:10.1136/bcr-2023-257569

Case of primary low-grade neuroendocrine carcinoma of the skin

Sara Krogh, Mette Bak Nielsen, Linda Skibsted Kornerup, Gitte Dam

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

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Abstract

A man presents a 4 mm skin tumour at his general practitioner. The tumour is removed on the suspicion of a dermatofibroma. Important differential diagnoses are sebaceous neoplasms, melanomas, Merkel cell carcinomas and large cell neuroendocrine carcinoma, and metastases of neuroendocrine neoplasms from the gut or lung. Immunohistochemical staining excluded sebaceous neoplasm, melanoma and Merkel cell carcinoma, however, was positive for multiple neuroendocrine markers. Relevant scans showed no signs of a primary tumour anywhere else. The final diagnosis was a primary low-grade neuroendocrine carcinoma of the skin. At 30 months follow-up, there was no sign of recurrence.

Original language	English
Article number	e257569
Journal	BMJ Case Reports
Volume	16
Issue	12
ISSN	1757-790X
DOIs	https://doi.org/10.1136/bcr-2023-257569
Publication status	Published - Dec 2023

Keywords

Dermatology
Neuroendocrinology
Pathology

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e257569.fullFinal published version, 1.41 MBLicence: CC BY-NC

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title = "Case of primary low-grade neuroendocrine carcinoma of the skin",

abstract = "A man presents a 4 mm skin tumour at his general practitioner. The tumour is removed on the suspicion of a dermatofibroma. Important differential diagnoses are sebaceous neoplasms, melanomas, Merkel cell carcinomas and large cell neuroendocrine carcinoma, and metastases of neuroendocrine neoplasms from the gut or lung. Immunohistochemical staining excluded sebaceous neoplasm, melanoma and Merkel cell carcinoma, however, was positive for multiple neuroendocrine markers. Relevant scans showed no signs of a primary tumour anywhere else. The final diagnosis was a primary low-grade neuroendocrine carcinoma of the skin. At 30 months follow-up, there was no sign of recurrence.",

keywords = "Dermatology, Neuroendocrinology, Pathology",

author = "Sara Krogh and {Bak Nielsen}, Mette and Kornerup, {Linda Skibsted} and Gitte Dam",

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T1 - Case of primary low-grade neuroendocrine carcinoma of the skin

AU - Krogh, Sara

AU - Bak Nielsen, Mette

AU - Kornerup, Linda Skibsted

AU - Dam, Gitte

N1 - Publisher Copyright: © BMJ Publishing Group Limited 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2023/12

Y1 - 2023/12

N2 - A man presents a 4 mm skin tumour at his general practitioner. The tumour is removed on the suspicion of a dermatofibroma. Important differential diagnoses are sebaceous neoplasms, melanomas, Merkel cell carcinomas and large cell neuroendocrine carcinoma, and metastases of neuroendocrine neoplasms from the gut or lung. Immunohistochemical staining excluded sebaceous neoplasm, melanoma and Merkel cell carcinoma, however, was positive for multiple neuroendocrine markers. Relevant scans showed no signs of a primary tumour anywhere else. The final diagnosis was a primary low-grade neuroendocrine carcinoma of the skin. At 30 months follow-up, there was no sign of recurrence.

AB - A man presents a 4 mm skin tumour at his general practitioner. The tumour is removed on the suspicion of a dermatofibroma. Important differential diagnoses are sebaceous neoplasms, melanomas, Merkel cell carcinomas and large cell neuroendocrine carcinoma, and metastases of neuroendocrine neoplasms from the gut or lung. Immunohistochemical staining excluded sebaceous neoplasm, melanoma and Merkel cell carcinoma, however, was positive for multiple neuroendocrine markers. Relevant scans showed no signs of a primary tumour anywhere else. The final diagnosis was a primary low-grade neuroendocrine carcinoma of the skin. At 30 months follow-up, there was no sign of recurrence.

KW - Dermatology

KW - Neuroendocrinology

KW - Pathology

U2 - 10.1136/bcr-2023-257569

DO - 10.1136/bcr-2023-257569

M3 - Journal article

C2 - 38110346

AN - SCOPUS:85180416475

SN - 1757-790X

VL - 16

JO - BMJ Case Reports

JF - BMJ Case Reports

IS - 12

M1 - e257569

ER -

Case of primary low-grade neuroendocrine carcinoma of the skin

Abstract

Keywords

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