Can a Charged Surfactant Unfold an Uncharged Protein?

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Can a Charged Surfactant Unfold an Uncharged Protein? / Højgaard, Casper; Sørensen, Henrik Vinther; Pedersen, Jan Skov; Winther, Jakob Rahr; Otzen, Daniel Erik.

In: Biophysical Journal, Vol. 115, No. 11, 04.12.2018, p. 2081-2086.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Højgaard, C, Sørensen, HV, Pedersen, JS, Winther, JR & Otzen, DE 2018, 'Can a Charged Surfactant Unfold an Uncharged Protein?', Biophysical Journal, vol. 115, no. 11, pp. 2081-2086. https://doi.org/10.1016/j.bpj.2018.10.022

APA

CBE

MLA

Højgaard, Casper et al. "Can a Charged Surfactant Unfold an Uncharged Protein?". Biophysical Journal. 2018, 115(11). 2081-2086. https://doi.org/10.1016/j.bpj.2018.10.022

Vancouver

Author

Højgaard, Casper ; Sørensen, Henrik Vinther ; Pedersen, Jan Skov ; Winther, Jakob Rahr ; Otzen, Daniel Erik. / Can a Charged Surfactant Unfold an Uncharged Protein?. In: Biophysical Journal. 2018 ; Vol. 115, No. 11. pp. 2081-2086.

Bibtex

@article{6fa1caedc5e24afa9e5882764ebfeb8b,
title = "Can a Charged Surfactant Unfold an Uncharged Protein?",
abstract = "Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.",
author = "Casper H{\o}jgaard and S{\o}rensen, {Henrik Vinther} and Pedersen, {Jan Skov} and Winther, {Jakob Rahr} and Otzen, {Daniel Erik}",
note = "Copyright {\textcopyright} 2018 Biophysical Society. Published by Elsevier Inc. All rights reserved.",
year = "2018",
month = dec,
day = "4",
doi = "10.1016/j.bpj.2018.10.022",
language = "English",
volume = "115",
pages = "2081--2086",
journal = "Biophysical Journal",
issn = "0006-3495",
publisher = "Cell Press",
number = "11",

}

RIS

TY - JOUR

T1 - Can a Charged Surfactant Unfold an Uncharged Protein?

AU - Højgaard, Casper

AU - Sørensen, Henrik Vinther

AU - Pedersen, Jan Skov

AU - Winther, Jakob Rahr

AU - Otzen, Daniel Erik

N1 - Copyright © 2018 Biophysical Society. Published by Elsevier Inc. All rights reserved.

PY - 2018/12/4

Y1 - 2018/12/4

N2 - Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.

AB - Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.

U2 - 10.1016/j.bpj.2018.10.022

DO - 10.1016/j.bpj.2018.10.022

M3 - Journal article

C2 - 30447995

VL - 115

SP - 2081

EP - 2086

JO - Biophysical Journal

JF - Biophysical Journal

SN - 0006-3495

IS - 11

ER -