You are here:
» Can a Charged Surfactant Unfold an Uncharged Protein?
About Aarhus University
Can a Charged Surfactant Unfold an Uncharged Protein?
Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
DOI
- https://doi.org/10.1016/j.bpj.2018.10.022
Final published version
- Casper Højgaard, University of Copenhagen ,
- Henrik Vinther Sørensen ,
- Jan Skov Pedersen
- Jakob Rahr Winther, University of Copenhagen ,
- Daniel Erik Otzen
Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.
| Original language | English |
|---|---|
| Journal | Biophysical Journal |
| Volume | 115 |
| Issue | 11 |
| Pages (from-to) | 2081-2086 |
| Number of pages | 6 |
| ISSN | 0006-3495 |
| DOIs | |
| Publication status | Published - 4 Dec 2018 |
See relations at Aarhus University Citationformats
ID: 136619544