Research output: Contribution to book/anthology/report/proceeding › Article in proceedings › Research › peer-review

- https://doi.org/10.4230/LIPIcs.WABI.2019.1
Final published version

- Jesper Jansson, Hong Kong Polytechnic University ,
- Konstantinos Mampentzidis
- T. P. Sandhya, Hong Kong Polytechnic University

We combine two fundamental, previously studied optimization problems related to the construction of phylogenetic trees called maximum rooted triplets consistency (MAXRTC) and minimally resolved supertree (MINRS) into a new problem, which we call q-maximum rooted triplets consistency (q-MAXRTC). The input to our new problem is a set R of resolved triplets (rooted, binary phylogenetic trees with three leaves each) and the objective is to find a phylogenetic tree with exactly q internal nodes that contains the largest possible number of triplets from R. We first prove that q-MAXRTC is NP-hard even to approximate within a constant ratio for every fixed q ≥ 2, and then develop various polynomial-time approximation algorithms for different values of q. Next, we show experimentally that representing a phylogenetic tree by one having much fewer nodes typically does not destroy too much triplet branching information. As an extreme example, we show that allowing only nine internal nodes is still sufficient to capture on average 80% of the rooted triplets from some recently published trees, each having between 760 and 3081 internal nodes. Finally, to demonstrate the algorithmic advantage of using trees with few internal nodes, we propose a new algorithm for computing the rooted triplet distance between two phylogenetic trees over a leaf label set of size n that runs in O(qn) time, where q is the number of internal nodes in the smaller tree, and is therefore faster than the currently best algorithms for the problem (with O(n log n) time complexity [SODA 2013, ESA 2017]) whenever q = o(log n).

Original language | English |
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Title of host publication | 19th International Workshop on Algorithms in Bioinformatics, WABI 2019 |

Editors | Katharina T. Huber, Dan Gusfield |

Number of pages | 14 |

Publisher | Schloss Dagstuhl- Leibniz-Zentrum fur Informatik GmbH, Dagstuhl Publishing |

Publication year | Sep 2019 |

Article number | 1 |

ISBN (Electronic) | 9783959771238 |

DOIs | |

Publication status | Published - Sep 2019 |

Event | 19th International Workshop on Algorithms in Bioinformatics, WABI 2019 - Niagara Falls, United States Duration: 8 Sep 2019 → 10 Sep 2019 |

Conference | 19th International Workshop on Algorithms in Bioinformatics, WABI 2019 |
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Land | United States |

By | Niagara Falls |

Periode | 08/09/2019 → 10/09/2019 |

Series | Leibniz International Proceedings in Informatics, LIPIcs |
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Volume | 143 |

ISSN | 1868-8969 |

- Approximation algorithm, Phylogenetic tree, Rooted triplet, Supertree

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