Brug af glykeret hæmoglobin-måling i praksis

Silje H. Christensen; Nete Hornung; Jurgita Janukonyté; Else Marie Vestergaard; Mie Samson

Brug af glykeret hæmoglobin-måling i praksis

Silje H. Christensen^*, Nete Hornung, Jurgita Janukonyté, Else Marie Vestergaard, Mie Samson

^*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Review › Research › peer-review

Abstract

Haemoglobin A1c (HbA1c) reflects the glycaemic status of the latest 2-3 month and is used in both diagnosing and monitoring diabetes. Different circumstances may lead to spurious HbA1c results as summarised in this review. HbA1c is susceptible to changes in erythrocyte turnover (e.g. anaemia) regardless of measurement method, and to analytical interference (e.g. haemoglobin variants) depending on the method. The laboratory may detect and warn of suspected analytical interference. However, if the clinical presentation and glycaemic measures are incoherent, spurious HbA1c should be suspected and fasting glucose should be measured.

Translated title of the contribution	Haemoglobin A_1c measurements when to use and when not
Original language	English
Journal	Ugeskrift for Læger
Volume	183
Issue	11
Number of pages	8
ISSN	0041-5782
Publication status	Published - Mar 2021

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abstract = "Haemoglobin A1c (HbA1c) reflects the glycaemic status of the latest 2-3 month and is used in both diagnosing and monitoring diabetes. Different circumstances may lead to spurious HbA1c results as summarised in this review. HbA1c is susceptible to changes in erythrocyte turnover (e.g. anaemia) regardless of measurement method, and to analytical interference (e.g. haemoglobin variants) depending on the method. The laboratory may detect and warn of suspected analytical interference. However, if the clinical presentation and glycaemic measures are incoherent, spurious HbA1c should be suspected and fasting glucose should be measured.",

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T1 - Brug af glykeret hæmoglobin-måling i praksis

AU - Christensen, Silje H.

AU - Hornung, Nete

AU - Janukonyté, Jurgita

AU - Vestergaard, Else Marie

AU - Samson, Mie

PY - 2021/3

Y1 - 2021/3

N2 - Haemoglobin A1c (HbA1c) reflects the glycaemic status of the latest 2-3 month and is used in both diagnosing and monitoring diabetes. Different circumstances may lead to spurious HbA1c results as summarised in this review. HbA1c is susceptible to changes in erythrocyte turnover (e.g. anaemia) regardless of measurement method, and to analytical interference (e.g. haemoglobin variants) depending on the method. The laboratory may detect and warn of suspected analytical interference. However, if the clinical presentation and glycaemic measures are incoherent, spurious HbA1c should be suspected and fasting glucose should be measured.

AB - Haemoglobin A1c (HbA1c) reflects the glycaemic status of the latest 2-3 month and is used in both diagnosing and monitoring diabetes. Different circumstances may lead to spurious HbA1c results as summarised in this review. HbA1c is susceptible to changes in erythrocyte turnover (e.g. anaemia) regardless of measurement method, and to analytical interference (e.g. haemoglobin variants) depending on the method. The laboratory may detect and warn of suspected analytical interference. However, if the clinical presentation and glycaemic measures are incoherent, spurious HbA1c should be suspected and fasting glucose should be measured.

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M3 - Review

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SN - 0041-5782

VL - 183

JO - Ugeskrift for Læger

JF - Ugeskrift for Læger

IS - 11

ER -

Brug af glykeret hæmoglobin-måling i praksis

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