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Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study

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  • Mahesh P Kate
  • ,
  • Mikkel B Hansen
  • Kim Mouridsen
  • Leif Østergaard
  • Victor Choi
  • ,
  • Bronwen E Gould
  • ,
  • Rebecca McCourt
  • ,
  • Michael D Hill
  • ,
  • Andrew M Demchuk
  • ,
  • Shelagh B Coutts
  • ,
  • Dariush Dowlatshahi
  • ,
  • Derek J Emery
  • ,
  • Brian H Buck
  • ,
  • Kenneth S Butcher
Blood pressure (BP) reduction after intracerebral hemorrhage (ICH) is controversial, because of concerns that this may cause critical reductions in perihematoma perfusion and thereby precipitate tissue damage. We tested the hypothesis that BP reduction reduces perihematoma tissue oxygenation.Acute ICH patients were randomized to a systolic BP target of
Original languageEnglish
JournalJournal of Cerebral Blood Flow and Metabolism
Volume34
Issue1
Pages (from-to)81-86
Number of pages6
ISSN0271-678X
DOIs
Publication statusPublished - 3 Jan 2014

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