Blodtransfusion øger den kirurgiske infektionsrisiko.

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In a prospective randomized trial the frequency of infectious complications and natural killer cell function were investigated in 197 patients undergoing elective colorectal surgery and having either no blood transfusion (n = 93), transfusion with whole blood (n = 56), or filtered blood free from leucocytes (n = 48). Postoperative infections developed in 13 patients transfused with whole blood (23%), in one patient transfused with blood free from leucocytes (2%) and in two non-transfused patients (2%) (p <0.01). Natural killer cell function was significantly (p <0.001) impaired up to 30 days after surgery in patients transfused with whole blood. These data provide a strong case against the use of whole blood transfusion in patients undergoing elective colorectal surgery.
Original languageEnglish
JournalUgeskrift for Laeger
Pages (from-to)3263-3266
Number of pages4
Publication statusPublished - 11 Oct 1993

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