TY - JOUR
T1 - Banking feces
T2 - a new frontier for public blood banks?
AU - Jørgensen, Simon Mark Dahl
AU - Hvas, Christian Lodberg
AU - Dahlerup, Jens Frederik
AU - Mikkelsen, Susan
AU - Ehlers, Lars
AU - Hammeken, Lianna Hede
AU - Licht, Tine Rask
AU - Bahl, Martin Iain
AU - Erikstrup, Christian
N1 - © 2019 The Authors. Transfusion published by Wiley Periodicals, Inc. on behalf of AABB.
PY - 2019
Y1 - 2019
N2 - Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection and is potentially beneficial in other microbiota-related disorders. The provision of FMT in routine clinical practice requires an extensive infrastructure that is reliant on voluntary donors. Alongside an increasing demand for FMT, the logistic barriers of a large-scale donor-dependent operation and the difficulties among health authorities to regulate FMT limit the dissemination of sustainable FMT services. Blood centers are large organizations that handle a multitude of donor-dependent operations on a daily basis. Blood and feces share many of the same dependencies, and feces may present a new opportunity for the blood services to handle. In this paper, we describe how an FMT service may be established and embedded within the blood service infrastructure, and we explain the benefits of using blood donors as feces donors. We further explore the current indications of FMT, the challenges related to the lack of legislation, and the future perspectives for blood banks to meet a new and increasing demand.
AB - Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection and is potentially beneficial in other microbiota-related disorders. The provision of FMT in routine clinical practice requires an extensive infrastructure that is reliant on voluntary donors. Alongside an increasing demand for FMT, the logistic barriers of a large-scale donor-dependent operation and the difficulties among health authorities to regulate FMT limit the dissemination of sustainable FMT services. Blood centers are large organizations that handle a multitude of donor-dependent operations on a daily basis. Blood and feces share many of the same dependencies, and feces may present a new opportunity for the blood services to handle. In this paper, we describe how an FMT service may be established and embedded within the blood service infrastructure, and we explain the benefits of using blood donors as feces donors. We further explore the current indications of FMT, the challenges related to the lack of legislation, and the future perspectives for blood banks to meet a new and increasing demand.
UR - http://www.scopus.com/inward/record.url?scp=85068378567&partnerID=8YFLogxK
U2 - 10.1111/trf.15422
DO - 10.1111/trf.15422
M3 - Journal article
C2 - 31241182
SN - 0041-1132
VL - 59
SP - 2776
EP - 2782
JO - Transfusion
JF - Transfusion
IS - 9
ER -