Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)

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  • Lisa D Wiggins, Denmark
  • Susan E Levy, Denmark
  • Julie Daniels, Denmark
  • Laura Schieve
  • ,
  • Lisa A Croen, Denmark
  • Carolyn DiGuiseppi, Denmark
  • Lisa Blaskey, Denmark
  • Ellen Giarelli, Denmark
  • Li-Ching Lee, Denmark
  • Jennifer Pinto-Martin, Denmark
  • Ann Reynolds, Denmark
  • Catherine Rice
  • ,
  • Cordelia Robinson Rosenberg, Denmark
  • Patrick Thompson, Denmark
  • Marshalyn Yeargin-Allsopp
  • ,
  • Lisa Young, Denmark
  • Diana Schendel

This study examined the phenotypic profiles of children aged 30-68 months in the Study to Explore Early Development (SEED). Children classified as autism spectrum disorder (ASD), developmental delay (DD) with ASD symptoms, DD without ASD symptoms, and population comparison (POP) differed significantly from each other on cognitive, adaptive, behavioral, and social functioning and the presence of parent-reported conditions. Children with ASD and DD with ASD symptoms had mild to severe ASD risk on several measures compared to children with other DD and POP who had little ASD risk across measures. We conclude that children in SEED have varying degrees of ASD impairment and associated deficits. SEED thus provides a valuable sample to explore ASD phenotypes and inform risk factor analyses.

Original languageEnglish
JournalJournal of Autism and Developmental Disorders
Pages (from-to)3183-94
Number of pages12
Publication statusPublished - Oct 2015

    Research areas

  • autism, etiology, symptoms, phenotype, study to explore early development

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