Atomic-scale structures and interactions between the guanine quartet and potassium

Wei Xu, Qinggang Tan, Miao Yu, Qiang Sun, Huihui Kong, Erik Lægsgaard, Ivan Stensgaard, Jørgen Kjems, Jian-guo Wang, Chen Wang, Flemming Besenbacher

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Abstract

The atomic-scale identification of the G4K1 structural motif is achieved using an interplay of STM imaging and DFT calculations. Its high stability is found to be caused by the delicate balance between hydrogen bonding and metal-ligand interaction, which is of utmost relevance to model interactions of the G-quadruplex with cations in vivo.
Original languageEnglish
JournalChemical Communications
Volume49
Issue65
Pages (from-to)7210-7212
Number of pages3
ISSN1359-7345
DOIs
Publication statusPublished - 21 Aug 2013

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