Association mapping and disease: evolutionary perspectives

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In this chapter, we give a short introduction to the genetics of complex disease with special emphasis on evolutionary models for disease genes and the effect of different models on the genetic architecture, and finally give a survey of the state-of-the-art of genome-wide association studies.
Original languageEnglish
JournalMethods in Molecular Biology
Pages (from-to)275-91
Number of pages17
Publication statusPublished - 2012

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