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Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe

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Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe. / Schmidtmann, Christin; Schönherz, Anna; Guldbrandtsen, Bernt et al.

In: Genetics Selection Evolution, Vol. 53, No. 1, 23, 2021.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Schmidtmann, C, Schönherz, A, Guldbrandtsen, B, Marjanovic, J, Calus, M, Hinrichs, D & Thaller, G 2021, 'Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe', Genetics Selection Evolution, vol. 53, no. 1, 23. https://doi.org/10.1186/s12711-021-00613-6

APA

Schmidtmann, C., Schönherz, A., Guldbrandtsen, B., Marjanovic, J., Calus, M., Hinrichs, D., & Thaller, G. (2021). Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe. Genetics Selection Evolution, 53(1), [23]. https://doi.org/10.1186/s12711-021-00613-6

CBE

Schmidtmann C, Schönherz A, Guldbrandtsen B, Marjanovic J, Calus M, Hinrichs D, Thaller G. 2021. Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe. Genetics Selection Evolution. 53(1):Article 23. https://doi.org/10.1186/s12711-021-00613-6

MLA

Vancouver

Schmidtmann C, Schönherz A, Guldbrandtsen B, Marjanovic J, Calus M, Hinrichs D et al. Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe. Genetics Selection Evolution. 2021;53(1):23. doi: 10.1186/s12711-021-00613-6

Author

Schmidtmann, Christin ; Schönherz, Anna ; Guldbrandtsen, Bernt et al. / Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe. In: Genetics Selection Evolution. 2021 ; Vol. 53, No. 1.

Bibtex

@article{7a46a857507f4dacafca52c20f09d331,
title = "Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe",
abstract = "Background: Local cattle breeds need special attention, as they are valuable reservoirs of genetic diversity. Appropriate breeding decisions and adequate genomic management of numerically smaller populations are required for their conservation. At this point, the analysis of dense genome-wide marker arrays provides encompassing insights into the genomic constitution of livestock populations. We have analyzed the genetic characterization of ten cattle breeds originating from Germany, The Netherlands and Denmark belonging to the group of red dairy breeds in Northern Europe. The results are intended to provide initial evidence on whether joint genomic breeding strategies of these populations will be successful. Results: Traditional Danish Red and Groningen White-Headed were the most genetically differentiated breeds and their populations showed the highest levels of inbreeding. In contrast, close genetic relationships and shared ancestry were observed for the populations of German Red and White Dual-Purpose, Dutch Meuse-Rhine-Yssel, and Dutch Deep Red breeds, reflecting their common histories. A considerable amount of gene flow from Red Holstein to German Angler and to German Red and White Dual-Purpose was revealed, which is consistent with frequent crossbreeding to improve productivity of these local breeds. In Red Holstein, marked genomic signatures of selection were reported on chromosome 18, suggesting directed selection for important breeding goal traits. Furthermore, tests for signatures of selection between Red Holstein, Red and White Dual-Purpose, and Meuse-Rhine-Yssel uncovered signals for all investigated pairs of populations. The corresponding genomic regions, which were putatively under different selection pressures, harboured various genes which are associated with traits such as milk and beef production, mastitis and female fertility. Conclusions: This study provides comprehensive knowledge on the genetic constitution and genomic connectedness of divergent red cattle populations in Northern Europe. The results will help to design and optimize breeding strategies. A joint genomic evaluation including some of the breeds studied here seems feasible.",
author = "Christin Schmidtmann and Anna Sch{\"o}nherz and Bernt Guldbrandtsen and Jovana Marjanovic and Mario Calus and Dirk Hinrichs and Georg Thaller",
note = "Funding Information: The authors acknowledge the Centre for Genetic Resources of The Netherlands (CGN) of Wageningen University and Research for providing the data of the Dutch breeds. The genotype data of the German breeds were gratefully contributed by the breeding organization Rinderzucht Schleswig-Holstein e.G. The authors acknowledge Aarhus University for providing the genotypes of the Danish cattle breed. Publisher Copyright: {\textcopyright} 2021, The Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
doi = "10.1186/s12711-021-00613-6",
language = "English",
volume = "53",
journal = "Genetics Selection Evolution",
issn = "0999-193X",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Assessing the genetic background and genomic relatedness of red cattle populations originating from Northern Europe

AU - Schmidtmann, Christin

AU - Schönherz, Anna

AU - Guldbrandtsen, Bernt

AU - Marjanovic, Jovana

AU - Calus, Mario

AU - Hinrichs, Dirk

AU - Thaller, Georg

N1 - Funding Information: The authors acknowledge the Centre for Genetic Resources of The Netherlands (CGN) of Wageningen University and Research for providing the data of the Dutch breeds. The genotype data of the German breeds were gratefully contributed by the breeding organization Rinderzucht Schleswig-Holstein e.G. The authors acknowledge Aarhus University for providing the genotypes of the Danish cattle breed. Publisher Copyright: © 2021, The Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021

Y1 - 2021

N2 - Background: Local cattle breeds need special attention, as they are valuable reservoirs of genetic diversity. Appropriate breeding decisions and adequate genomic management of numerically smaller populations are required for their conservation. At this point, the analysis of dense genome-wide marker arrays provides encompassing insights into the genomic constitution of livestock populations. We have analyzed the genetic characterization of ten cattle breeds originating from Germany, The Netherlands and Denmark belonging to the group of red dairy breeds in Northern Europe. The results are intended to provide initial evidence on whether joint genomic breeding strategies of these populations will be successful. Results: Traditional Danish Red and Groningen White-Headed were the most genetically differentiated breeds and their populations showed the highest levels of inbreeding. In contrast, close genetic relationships and shared ancestry were observed for the populations of German Red and White Dual-Purpose, Dutch Meuse-Rhine-Yssel, and Dutch Deep Red breeds, reflecting their common histories. A considerable amount of gene flow from Red Holstein to German Angler and to German Red and White Dual-Purpose was revealed, which is consistent with frequent crossbreeding to improve productivity of these local breeds. In Red Holstein, marked genomic signatures of selection were reported on chromosome 18, suggesting directed selection for important breeding goal traits. Furthermore, tests for signatures of selection between Red Holstein, Red and White Dual-Purpose, and Meuse-Rhine-Yssel uncovered signals for all investigated pairs of populations. The corresponding genomic regions, which were putatively under different selection pressures, harboured various genes which are associated with traits such as milk and beef production, mastitis and female fertility. Conclusions: This study provides comprehensive knowledge on the genetic constitution and genomic connectedness of divergent red cattle populations in Northern Europe. The results will help to design and optimize breeding strategies. A joint genomic evaluation including some of the breeds studied here seems feasible.

AB - Background: Local cattle breeds need special attention, as they are valuable reservoirs of genetic diversity. Appropriate breeding decisions and adequate genomic management of numerically smaller populations are required for their conservation. At this point, the analysis of dense genome-wide marker arrays provides encompassing insights into the genomic constitution of livestock populations. We have analyzed the genetic characterization of ten cattle breeds originating from Germany, The Netherlands and Denmark belonging to the group of red dairy breeds in Northern Europe. The results are intended to provide initial evidence on whether joint genomic breeding strategies of these populations will be successful. Results: Traditional Danish Red and Groningen White-Headed were the most genetically differentiated breeds and their populations showed the highest levels of inbreeding. In contrast, close genetic relationships and shared ancestry were observed for the populations of German Red and White Dual-Purpose, Dutch Meuse-Rhine-Yssel, and Dutch Deep Red breeds, reflecting their common histories. A considerable amount of gene flow from Red Holstein to German Angler and to German Red and White Dual-Purpose was revealed, which is consistent with frequent crossbreeding to improve productivity of these local breeds. In Red Holstein, marked genomic signatures of selection were reported on chromosome 18, suggesting directed selection for important breeding goal traits. Furthermore, tests for signatures of selection between Red Holstein, Red and White Dual-Purpose, and Meuse-Rhine-Yssel uncovered signals for all investigated pairs of populations. The corresponding genomic regions, which were putatively under different selection pressures, harboured various genes which are associated with traits such as milk and beef production, mastitis and female fertility. Conclusions: This study provides comprehensive knowledge on the genetic constitution and genomic connectedness of divergent red cattle populations in Northern Europe. The results will help to design and optimize breeding strategies. A joint genomic evaluation including some of the breeds studied here seems feasible.

UR - http://www.scopus.com/inward/record.url?scp=85102206957&partnerID=8YFLogxK

U2 - 10.1186/s12711-021-00613-6

DO - 10.1186/s12711-021-00613-6

M3 - Journal article

C2 - 33676402

AN - SCOPUS:85102206957

VL - 53

JO - Genetics Selection Evolution

JF - Genetics Selection Evolution

SN - 0999-193X

IS - 1

M1 - 23

ER -