Aquagenic wrinkling of the palms is a rare dermatological disease associated with cystic fibrosis

Anne Sofie Frølunde, Lise Graversen, Kristine Appel Uldall Pallesen, Mette Sommerlund

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

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Abstract

Aquagenic wrinkling of the palms was first described in 1974. This review summarises the present knowledge. Aquagenic wrinkling of the palms is most often associated with cystic fibrosis, but several other associated conditions are described. Patients report of pruritus, pain and discomfort in the palms after contact with water, and excessive wrinkling is visible. The prognosis is good, and symptoms often decrease in adulthood. A positive water exposure test will support the diagnosis, and the patient should be referred for dermatological investigation and genetic test for cystic fibrosis should be offered.

Original languageEnglish
JournalUgeskrift for Læger
Volume183
Issue19
ISSN0041-5782
Publication statusPublished - 10 May 2021

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