Apparent diffusion coefficients in GEC ESTRO target volumes for image guided adaptive brachytherapy of locally advanced cervical cancer

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  • MTA
  • Center of Magnetic Resonance
  • The Department of Oncology
  • Diagnostic Radiology
  • Center for Functionally Integrative Neuroscience
  • Afdeling for Medicinsk Fysik
T2 weighted MRI is recommended for image guided adaptive brachytherapy (IGABT) in cervical cancer. Diffusion weighted imaging (DWI) and the derived apparent diffusion coefficient (ADC) may add additional biological information on tumour cell density. The purpose of this study was to evaluate the distribution of the ADC within target volumes as recommended by GEC-ESTRO: Gross Tumour Volume at BT (GTV(BT)), High-Risk Clinical Tumour Volume (HR-CTV) and Intermediate-Risk Clinical Target Volume (IR-CTV) and to evaluate the change of diffusion between fractions of IGABT.
Original languageEnglish
JournalActa Oncologica
Volume49
Issue7
Pages (from-to)978-83
Number of pages6
ISSN0284-186X
DOIs
Publication statusPublished - 1 Oct 2010

    Research areas

  • Brachytherapy, Carcinoma, Adenosquamous, Carcinoma, Squamous Cell, Diffusion, Diffusion Magnetic Resonance Imaging, Disease Progression, Dose Fractionation, Female, Guidelines as Topic, Humans, Image Processing, Computer-Assisted, Models, Theoretical, Neoplasm Staging, Organ Size, Radiation Dosage, Radiotherapy Planning, Computer-Assisted, Tumor Burden, Uterine Cervical Neoplasms

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