Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati

Translated title of the contribution: Antibodies in patients with chronic inflammatory demyelinating polyneuropathy

Abdullahi Mohamed, Thomas Krøigård, Thomas Agerbo Gaist, Lars Kjøbsted Markvardsen, Søren Sindrup, Henning Andersen, Morten Blaabjerg

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

Abstract

Recent studies have identified specific immunoglobulin (Ig) G4 antibodies against the paranodal proteins neurofascin 155 and contactin 1 in subgroups of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). These patients present with distinct clinical phenotypes and poor response to first-line therapy with intravenous Ig. Detection of these antibodies in patients with CIDP has diagnostic, prognostic, and therapeutic implications. This review summarises the current knowledge on clinical characteristics, pathogenesis and treatment of these patients.

Translated title of the contributionAntibodies in patients with chronic inflammatory demyelinating polyneuropathy
Original languageDanish
Article numberV08180526
JournalUgeskrift for Læger
Volume180
ISSN0041-5782
Publication statusPublished - 3 Dec 2018

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