Antirotaviral Activity of Bovine and Ovine Dairy Byproducts

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DOI

  • José Antonio Parrón, Departamento de Anatomía, Embriología y Genética Animal, Facultad de Veterinaria, Universidad de Zaragoza
  • ,
  • Daniel Ripollés, Departamento de Anatomía, Embriología y Genética Animal, Facultad de Veterinaria, Universidad de Zaragoza
  • ,
  • María Dolores Pérez, Departamento de Producción Animal y Ciencia de los Alimentos, Departamento de Anatomía, Embriología y Genética Animal, Facultad de Veterinaria, Universidad de Zaragoza
  • ,
  • Miguel Calvo, Departamento de Anatomía, Embriología y Genética Animal, Facultad de Veterinaria, Universidad de Zaragoza
  • ,
  • Jan Trige Rasmussen
  • Lourdes Sánchez, Departamento de Anatomía, Embriología y Genética Animal, Facultad de Veterinaria, Universidad de Zaragoza

Rotaviral gastroenteritis is associated with significant morbidity in developed countries and a high rate of infant mortality in developing countries. Diverse studies have demonstrated that a wide range of milk-derived fractions exhibit antirotaviral activity. The present study shows the antirotaviral activity of some bovine and ovine dairy byproducts, buttermilk, butter serum, and milk fat globule membrane (MFGM), and evaluates the effect of cream washing and heat treatment on that activity. Furthermore, the rotavirus-neutralizing activity was evaluated for some MFGM proteins, such as xanthine oxidase and lactophorin. Ovine and bovine buttermilk reached rotavirus-neutralizing values of 51.3 and 32.2%, at 1 mg/mL, respectively. The cream washing process led to a significant decrease in the antirotaviral activity of fractions. This activity was also influenced by heat treatment. Treatment at 75 °C for 20 s caused 24.6 and 36.1% decreases of activity in bovine and ovine buttermilk, respectively, and 85 °C for 10 min caused decreases of 80.9 and 79.0% in both fractions, respectively.

Original languageEnglish
JournalJournal of Agricultural and Food Chemistry
Volume65
Issue21
Pages (from-to)4280-4288
Number of pages9
ISSN0021-8561
DOIs
Publication statusPublished - 31 May 2017

    Research areas

  • antirotaviral activity, butter serum, buttermilk, cream washing, dairy byproducts, heat treatment, lactophorin, milk fat globule membrane, xanthine oxidase

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