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Analysis of Migrant Cyclic PET Oligomers in Olive Oil and Food Simulants Using UHPLC-qTOF-MS

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  • Dimitra Diamantidou, Aristotle University of Thessaloniki, Balkan Center
  • ,
  • Emmanouil Tsochatzis
  • Stavros Kalogiannis, Balkan Center, International Hellenic University
  • ,
  • Joao Alberto Lopes, European Innovation Council and SMEs Executive Agency
  • ,
  • Georgios Theodoridis, Aristotle University of Thessaloniki, Balkan Center
  • ,
  • Helen Gika, Balkan Center, Aristotle University of Thessaloniki

Oligomers are a particular category of non-intentionally added substances (NIAS) that may be present in food contact materials (FCMs), such as polyethylene terephthalate (PET), and consequently migrate into foods. Here, an ultra-high-pressure liquid chromatography quadruple time-of-flight mass spectrometry (UHPLC-qTOF-MS) method was developed for the analysis of 1st series cyclic PET oligomers in virgin olive oil (VOO) following a QuEChERS clean-up protocol. Oligomer migration was evaluated with two different migration experiments using bottles from virgin and recycled PET: one with VOO samples stored in household conditions for a year and one using the food simulant D2 (95% v/v ethanol in water) at 60 °C for 10 days. Calibration curves were constructed with fortified VOO samples, with the LOQs ranging from 10 to 50 µg L−1 and the recoveries ranging from 86.6 to 113.0%. Results showed no migration of PET oligomers in VOO. However, in the simulated study, significant amounts of all oligomers were detected, with the migration of cyclic PET trimers from recycled bottles being the most abundant. Additional substances were tentatively identified as linear derivatives of PET oligomers. Again, open trimer structures in recycled bottles gave the most significant signals.

Original languageEnglish
Article number2739
Publication statusPublished - Jul 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

    Research areas

  • cyclic polyester oligomers, food contact materials (FCM), migration testing, quadrupole time-of-flight mass spectrometry (qTOF-MS), QuEChERS clean-up, ultra high-performance liquid chromatography (UHPLC)

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