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Final published version
Stress can affect the brain functionality in many ways. As the synaptic vesicles have a major role in nervous signal transportation in synapses, their distribution in relationship to the active zone is very important in studying the neuron responses. We study the effect of stress on brain functionality by statistically modelling the distribution of the synaptic vesicles in two groups of rats: A control group subjected to sham stress and a stressed group subjected to a single acute foot-shock (FS)-stress episode. We hypothesize that the synaptic vesicles have different spatial distributions in the two groups. The spatial distributions are modelled using spatial point process models with an inhomogeneous conditional intensity and repulsive pairwise interactions. Our results verify the hypothesis that the two groups have different spatial distributions.
Original language | English |
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Journal | ACM BCB 2014 - 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics |
Pages (from-to) | 73-78 |
Number of pages | 6 |
DOIs | |
Publication status | Published - 20 Sep 2014 |
Event | 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, ACM BCB 2014 - Newport Beach, United States Duration: 20 Sep 2014 → 23 Sep 2014 |
Conference | 5th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, ACM BCB 2014 |
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Country | United States |
City | Newport Beach |
Period | 20/09/2014 → 23/09/2014 |
Sponsor | ACM Special Interest Group on Biomedical Computing (SIGBIO) |
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