Martien A M Groenen, Animal Breeding and Genomics Centre, Wageningen University, Netherlands
Alan L Archibald, University of Edinburgh, United Kingdom
Hirohide Uenishi, National Institute of Agrobiological Sciences, Japan
Christopher K Tuggle, Iowa State University, United States
Yasuhiro Takeuchi, MRC/UCL Centre for Medical Molecular Virology and Wohl Virion Centre, Division of Infection & Immunity, University College London, United Kingdom
Max F Rothschild, Iowa State University, United States
Claire Rogel-Gaillard, INRA, Laboratory of Animal Genetics and Integrative Biology/AgroParisTech, Laboratory of Animal Genetics and Integrative Biology/CEA, DSV, IRCM, Laboratoire de Radiobiologie et Etude du Ge´nome, France
Chankyu Park, Department of Animal Biotechnology, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul, Korea, Republic of
Denis Milan, Aberystwyth University, United Kingdom
Hendrik-Jan Megens, Animal Breeding and Genomics Centre, Wageningen University, Netherlands
Shengting Li, Denmark
Denis M Larkin, Aberystwyth University, United Kingdom
Heebal Kim, Seoul National University, Korea, Republic of
Laurent A F Frantz, Animal Breeding and Genomics Centre, Wageningen University, Netherlands
Mario Caccamo, The Genome Analysis Centre, Norwich Research Park, United Kingdom
Hyeonju Ahn, Department of Agricultural Biotechnology and C&KGenomics, Seoul NationalUniversity, Korea, Republic of
Bronwen L Aken, Wellcome Sanger Institute, United Kingdom
Anna Anselmo, Parco Tecnologico Padano, Italy
Christian Anthon, University of Copenhagen, Denmark
Loretta Auvil, Illinois Informatics Institute, University of Illinois, United States
Bouabid Badaoui, Parco Tecnologico Padano, Italy
Craig W Beattie, Department of Surgery, University of Illinois, United States
Christian Bendixen, Denmark
Daniel Berman, 0USDA ARS BARC Animal Parasitic Diseases Laboratory, United States
Frank Blecha, Kansas State University, United States
Mirte Bosse, Animal Breeding and Genomics Centre, Wageningen University, Netherlands
Sara Botti, Parco Tecnologico Padano, Italy
Bujie Zhan
,
Megan Bystrom, Iowa State University, United States
Boris Capitanu, Illinois Informatics Institute, University of Illinois, United States
Denise Carvalho-Silva, European Bioinformatics Institute, Wellcome Trust Genome Campus, United Kingdom
Patrick Chardon, INRA, Laboratory of Animal Genetics and Integrative Biology/AgroParisTech, Laboratory of Animal Genetics and Integrative Biology, France
Celine Chen, Diet, Genomics, Immunology Laboratory, Beltsville Human Nutrition Research Center, United States Department of Agriculture, United States
Ryan Cheng, Iowa State University, United States
Sang-Haeng Choi, Korean Research Institute of Bioscience and Biotechnology, Korea, Republic of
William Chow, Wellcome Sanger Institute, United Kingdom
Richard C Clark, Wellcome Sanger Institute, United Kingdom
Christopher Clee, Wellcome Sanger Institute, United Kingdom
Richard P M A Crooijmans, Animal Breeding and Genomics Centre, Wageningen University, Netherlands
Harry D Dawson, Diet, Genomics, Immunology Laboratory, Beltsville Human Nutrition Research Center, United States Department of Agriculture, BARC-East, United States
Patrice Dehais, INRA, Laboratoire de Ge´ne´tique Cellulaire, Chemin de Borde-Rouge, France
Fioravante De Sapio, University of Edinburgh, United Kingdom
Bert Dibbits, Animal Breeding and Genomics Centre, Wageningen University, Netherlands
Nizar Drou, The Genome Analysis Centre, Norwich Research Park, United Kingdom
Zhi-Qiang Du, Iowa State University, United States
Kellye Eversole, Eversole Associates and the Alliance for Animal Genome Research, United States
João Fadista
,
Susan Fairley, Wellcome Sanger Institute, United Kingdom
Thomas Faraut, INRA, Laboratoire de Ge´ne´tique Cellulaire, Chemin de Borde-Rouge, France
Geoffrey J Faulkner, University of Edinburgh, United Kingdom
Katie E Fowler, University of Edinburgh, United Kingdom
Merete Fredholm, University of Copenhagen, Denmark
Eric Fritz, Iowa State University, United States
James G R Gilbert, Wellcome Sanger Institute, United Kingdom
Elisabetta Giuffra, INRA, Laboratory of Animal Genetics and Integrative Biology/AgroParisTech, Laboratory of Animal Genetics and Integrative Biology/CEA, DSV, IRCM, Laboratoire de Radiobiologie et Etude du Ge´nome, France
Jan Gorodkin, University of Copenhagen, Denmark
Darren K Griffin, School of Biosciences, The University of Kent, United Kingdom
Jennifer L Harrow, Wellcome Sanger Institute, United Kingdom
Alexander Hayward, Uppsala University, Sweden
Kerstin Howe, Wellcome Sanger Institute, United Kingdom
Zhi-Liang Hu, Iowa State University, United States
Sean J Humphray, Wellcome Sanger Institute, United Kingdom
Toby Hunt, Wellcome Sanger Institute, United Kingdom
Henrik Hornshøj, Denmark
Jin-Tae Jeon, Department of Animal Sciences, College of Agriculture and Life Sciences, Gyeongsang National University, Korea, Republic of
Patric Jern, Uppsala University, Sweden
Matthew Jones, Wellcome Sanger Institute, United Kingdom
Jerzy Jurka, Genetic Information Research Institute, United States
Hiroyuki Kanamori, National Institute of Agrobiological Sciences, Japan
Ronan Kapetanovic, University of Edinburgh, United Kingdom
Jaebum Kim, Department of Animal Biotechnology, Konkuk University, Korea, Republic of
Jae-Hwan Kim, Animal Genetic Resources Station, National Institute of Animal Science, Korea, Republic of
Kyu-Won Kim, C&K Genomics, Korea, Republic of
Tae-Hun Kim, 35Animal Genomics and Bioinformatics Division, National Institute of Animal Science, Korea, Republic of
Greger Larson, University of Durham, United Kingdom
Kyooyeol Lee, Department of Animal Biotechnology, Konkuk University, Korea, Republic of
Kyung-Tai Lee, C&K Genomics, Korea, Republic of
Richard Leggett, The Genome Analysis Centre, Norwich Research Park, United Kingdom
Harris A Lewin, Department of Evolution and Ecology, The UC Davis Genome Center, United States
Yingrui Li, BGI-Shenzhen, China
Wansheng Liu, Pennsylvania State University, United States
Jane E Loveland, Wellcome Sanger Institute, United Kingdom
Yao Lu, BGI-Shenzhen, China
Joan K Lunney, 0USDA ARS BARC Animal Parasitic Diseases Laboratory, United States
Jian Ma, Department of Bioengineering and Institute for Genomic Biology, University of Illinois, United States
Ole Madsen, Animal Breeding and Genomics Centre, Wageningen University, De Elst 1, 6708 WD, Wageningen, Netherlands
Katherine Mann, 0USDA ARS BARC Animal Parasitic Diseases Laboratory, United States
Lucy Matthews, Wellcome Sanger Institute, United Kingdom
Stuart McLaren, Wellcome Sanger Institute, United Kingdom
Takeya Morozumi, Institute of Japan Association for Techno-innovation in Agriculture, Forestry and Fisheries, Japan
Michael P Murtaugh, Department of Veterinary and Biomedical Sciences, University of Minnesota, United States
Jitendra Narayan, Aberystwyth University, United Kingdom
Dinh Truong Nguyen, Department of Animal Biotechnology, Konkuk University, Korea, Republic of
Peixiang Ni, BGI-Shenzhen, China
Song-Jung Oh, Jeju National University, Korea, Republic of
Suneel Onteru, Iowa State University, United States
Eung-Woo Park, Animal Genomics and Bioinformatics Division, National Institute of Animal Science, Korea, Republic of
Hong-Seog Park, Korean Research Institute of Bioscience and Biotechnology, Korea, Republic of
Geraldine Pascal, INRA UMR85/CNRS UMR7247 Physiologie de la Reproduction et des Comportements/IFCE, France
Yogesh Paudel, Animal Breeding and Genomics Centre, Wageningen University, Netherlands
Miguel Perez-Enciso, ICREA, Centre for Research in Agricultural Genomics (CRAG) and Facultat de Veterinaria UAB, Campus Universitat Autonoma Barcelona, Spain
Ricardo Ramirez-Gonzalez, The Genome Analysis Centre, Norwich Research Park, United Kingdom
James M Reecy, Iowa State University, United States
Sandra Rodriguez-Zas, Department of Animal Sciences, University of Illinois, United States
Gary A Rohrer, USDA, ARS, USMeat Animal Research Center, Clay Center, United States
Lauretta Rund, Department of Animal Sciences, University of Illinois, United States
Yongming Sang, Kansas State University, United States
Kyle Schachtschneider, Department of Animal Sciences, University of Illinois, United States
Joshua G Schraiber, Department of Integrative Biology, University of California, United States
John Schwartz, Department of Veterinary and Biomedical Sciences, University of Minnesota, United States
Linda Scobie, Department of Life Sciences, Glasgow Caledonian University, United Kingdom
Carol Scott, Wellcome Sanger Institute, United Kingdom
Stephen Searle, Wellcome Sanger Institute, United Kingdom
Bertrand Servin, INRA, Laboratoire de Ge´ne´tique Cellulaire, Chemin de Borde-Rouge, France
Bruce R Southey, Department of Animal Sciences, University of Illinois, United States
Goran Sperber, Uppsala University, Sweden
Peter Stadler, Bioinformatics Group, Department of Computer Science, Interdisciplinary Center for Bioinformatics, Universität Leipzig, Germany
Jonathan V Sweedler, Department of Chemistry, University of Illinois, United States
Hakim Tafer, Bioinformatics Group, Department of Computer Science, Interdisciplinary Center for Bioinformatics, Universität Leipzig, Germany
For 10,000 years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars ∼1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model.