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An unusual case of extreme thrombocytosis caused by iron deficiency. / Bergmann, Kristin; Bergmann, Olav J.
In: BMJ Case Reports, Vol. 13, No. 1, e231833, 01.2020.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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TY - JOUR
T1 - An unusual case of extreme thrombocytosis caused by iron deficiency
AU - Bergmann, Kristin
AU - Bergmann, Olav J.
PY - 2020/1
Y1 - 2020/1
N2 - Iron deficiency is a common cause of reactive thrombocytosis resulting in usually mild to moderately increased but sometimes even in extreme thrombocytosis (ie, >1000×10 9 /L). We report a case of a 34-year-old woman who developed an increased platelet count of 1953×10 9 /L. Upon admission, cytoreductive therapy was initiated until an underlying chronic myeloproliferative neoplasia was ruled out. The patient had undergone bariatric surgery 5 years previously, and surprisingly, a diagnosis of reactive thrombocytosis due to iron deficiency secondary to iron malabsorption was made. It is concluded that the degree of extreme thrombocytosis may be even fourfold to fivefold increased in patients with severe iron deficiency. Our finding emphasises the importance of regular control of possible need for iron supplementation following bariatric surgery.
AB - Iron deficiency is a common cause of reactive thrombocytosis resulting in usually mild to moderately increased but sometimes even in extreme thrombocytosis (ie, >1000×10 9 /L). We report a case of a 34-year-old woman who developed an increased platelet count of 1953×10 9 /L. Upon admission, cytoreductive therapy was initiated until an underlying chronic myeloproliferative neoplasia was ruled out. The patient had undergone bariatric surgery 5 years previously, and surprisingly, a diagnosis of reactive thrombocytosis due to iron deficiency secondary to iron malabsorption was made. It is concluded that the degree of extreme thrombocytosis may be even fourfold to fivefold increased in patients with severe iron deficiency. Our finding emphasises the importance of regular control of possible need for iron supplementation following bariatric surgery.
KW - haematology (incl blood transfusion)
KW - nutritional support
UR - http://www.scopus.com/inward/record.url?scp=85077679680&partnerID=8YFLogxK
U2 - 10.1136/bcr-2019-231833
DO - 10.1136/bcr-2019-231833
M3 - Journal article
C2 - 31919059
AN - SCOPUS:85077679680
VL - 13
JO - B M J Case Reports
JF - B M J Case Reports
SN - 1757-790X
IS - 1
M1 - e231833
ER -