An International Delphi-Based Study for Developing a Core Outcome Set for Hypospadias Surgery

Tina L Leunbach; Francisca Yankovic; Alexander Springer; Amy Wisniewski; Berk Burgu; Luis Braga; Andreas Ernst; Angela Lucas-Herald; Stuart O'Toole; S Faisal Ahmed; Yazan F Rawashdeh

doi:10.1159/000541596

An International Delphi-Based Study for Developing a Core Outcome Set for Hypospadias Surgery

Tina L Leunbach^*, Francisca Yankovic, Alexander Springer, Amy Wisniewski, Berk Burgu, Luis Braga, Andreas Ernst, Angela Lucas-Herald, Stuart O'Toole, S Faisal Ahmed, Yazan F Rawashdeh

^*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Abstract

INTRODUCTION: Explicit outcomes routinely measured across the life span following hypospadias surgery, defined by a core outcome set (COS), will harmonize and overcome reporting heterogeneity.

METHODS: Age-specific outcomes identified in a literature review were presented in a three-round Delphi survey. Participants (professionals, parents, and patients) were encouraged to suggest outcomes in the first Delphi round. In subsequent rounds, participants were asked to choose and rank up to five preferred outcomes for each age. To be deemed core, an outcome needed over 70% of votes in a round.

RESULTS: Professionals were mainly paediatric urologists (rounds 1, 2, 3: n = 57 [77%], 39 [78%], 35 [81%]). The response rates from parents/patients (rounds 1, 2, 3: n = 17, 5, 3) were low. In young boys (<6 years, 10-11 years), four core outcomes were identical (voiding, fistula, re-operation, and urethral stricture). Core outcomes in boys aged 11-16 years (cosmesis, curvature, voiding, stricture, and psychosocial status) and boys >16 years (cosmesis, curvature, erection, voiding, and psychosexual development) varied more.

CONCLUSION: Outcomes to include in a COS were consistent in younger boys. A larger variety was observed in older boys and reflects less clarity on relevant outcomes.

Original language	English
Journal	Sexual Development
Pages (from-to)	1-7
Number of pages	7
ISSN	1661-5425
DOIs	https://doi.org/10.1159/000541596
Publication status	E-pub / Early view - 18 Jan 2025

Keywords

Delphi study
hypospadias
long-term adverse effects
re-operation
treatment outcome

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10.1159/000541596

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title = "An International Delphi-Based Study for Developing a Core Outcome Set for Hypospadias Surgery",

abstract = "INTRODUCTION: Explicit outcomes routinely measured across the life span following hypospadias surgery, defined by a core outcome set (COS), will harmonize and overcome reporting heterogeneity.METHODS: Age-specific outcomes identified in a literature review were presented in a three-round Delphi survey. Participants (professionals, parents, and patients) were encouraged to suggest outcomes in the first Delphi round. In subsequent rounds, participants were asked to choose and rank up to five preferred outcomes for each age. To be deemed core, an outcome needed over 70% of votes in a round.RESULTS: Professionals were mainly paediatric urologists (rounds 1, 2, 3: n = 57 [77%], 39 [78%], 35 [81%]). The response rates from parents/patients (rounds 1, 2, 3: n = 17, 5, 3) were low. In young boys (<6 years, 10-11 years), four core outcomes were identical (voiding, fistula, re-operation, and urethral stricture). Core outcomes in boys aged 11-16 years (cosmesis, curvature, voiding, stricture, and psychosocial status) and boys >16 years (cosmesis, curvature, erection, voiding, and psychosexual development) varied more.CONCLUSION: Outcomes to include in a COS were consistent in younger boys. A larger variety was observed in older boys and reflects less clarity on relevant outcomes.",

keywords = "Delphi study, hypospadias, long-term adverse effects, re-operation, treatment outcome",

author = "Leunbach, {Tina L} and Francisca Yankovic and Alexander Springer and Amy Wisniewski and Berk Burgu and Luis Braga and Andreas Ernst and Angela Lucas-Herald and Stuart O'Toole and Ahmed, {S Faisal} and Rawashdeh, {Yazan F}",

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T1 - An International Delphi-Based Study for Developing a Core Outcome Set for Hypospadias Surgery

AU - Leunbach, Tina L

AU - Yankovic, Francisca

AU - Springer, Alexander

AU - Wisniewski, Amy

AU - Burgu, Berk

AU - Braga, Luis

AU - Ernst, Andreas

AU - Lucas-Herald, Angela

AU - O'Toole, Stuart

AU - Ahmed, S Faisal

AU - Rawashdeh, Yazan F

PY - 2025/1/18

Y1 - 2025/1/18

N2 - INTRODUCTION: Explicit outcomes routinely measured across the life span following hypospadias surgery, defined by a core outcome set (COS), will harmonize and overcome reporting heterogeneity.METHODS: Age-specific outcomes identified in a literature review were presented in a three-round Delphi survey. Participants (professionals, parents, and patients) were encouraged to suggest outcomes in the first Delphi round. In subsequent rounds, participants were asked to choose and rank up to five preferred outcomes for each age. To be deemed core, an outcome needed over 70% of votes in a round.RESULTS: Professionals were mainly paediatric urologists (rounds 1, 2, 3: n = 57 [77%], 39 [78%], 35 [81%]). The response rates from parents/patients (rounds 1, 2, 3: n = 17, 5, 3) were low. In young boys (<6 years, 10-11 years), four core outcomes were identical (voiding, fistula, re-operation, and urethral stricture). Core outcomes in boys aged 11-16 years (cosmesis, curvature, voiding, stricture, and psychosocial status) and boys >16 years (cosmesis, curvature, erection, voiding, and psychosexual development) varied more.CONCLUSION: Outcomes to include in a COS were consistent in younger boys. A larger variety was observed in older boys and reflects less clarity on relevant outcomes.

AB - INTRODUCTION: Explicit outcomes routinely measured across the life span following hypospadias surgery, defined by a core outcome set (COS), will harmonize and overcome reporting heterogeneity.METHODS: Age-specific outcomes identified in a literature review were presented in a three-round Delphi survey. Participants (professionals, parents, and patients) were encouraged to suggest outcomes in the first Delphi round. In subsequent rounds, participants were asked to choose and rank up to five preferred outcomes for each age. To be deemed core, an outcome needed over 70% of votes in a round.RESULTS: Professionals were mainly paediatric urologists (rounds 1, 2, 3: n = 57 [77%], 39 [78%], 35 [81%]). The response rates from parents/patients (rounds 1, 2, 3: n = 17, 5, 3) were low. In young boys (<6 years, 10-11 years), four core outcomes were identical (voiding, fistula, re-operation, and urethral stricture). Core outcomes in boys aged 11-16 years (cosmesis, curvature, voiding, stricture, and psychosocial status) and boys >16 years (cosmesis, curvature, erection, voiding, and psychosexual development) varied more.CONCLUSION: Outcomes to include in a COS were consistent in younger boys. A larger variety was observed in older boys and reflects less clarity on relevant outcomes.

KW - Delphi study

KW - hypospadias

KW - long-term adverse effects

KW - re-operation

KW - treatment outcome

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SN - 1661-5425

SP - 1

EP - 7

JO - Sexual Development

JF - Sexual Development

ER -

An International Delphi-Based Study for Developing a Core Outcome Set for Hypospadias Surgery

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