Allele Re-sequencing Technologies

Research output: Contribution to book/anthology/report/proceedingBook chapterResearchpeer-review

  • Stephen Byrne, Denmark
  • Jacqueline Danielle Farrell, Denmark
  • Torben Asp
The development of next-generation sequencing technologies has made sequencing an affordable approach for detection of genetic variations associated with various traits. However, the cost of whole genome re-sequencing still remains too high to be feasible for many plant species with large and complex genomes. Recent developments in strategies for target-enrichment, transcriptome re-sequencing, and partial genome re-sequencing allows for enrichment for regions of interest at a scale that is matched to the throughput of next-generation sequencing platforms, and has emerged as a promising alternative to whole genome re-sequencing to identify causative genetic variations in plants. One challenge, however, will be efficient bioinformatics strategies for data handling and analysis from the increasing amount of sequence information.
Original languageEnglish
Title of host publicationDiagnostics in Plant Breeding
EditorsThomas Lübberstedt, Rajeev K Varshney
Number of pages28
PublisherSpringer Science+Business Media
Publication year2013
Pages91-118
Chapter5
ISBN (print)978-94-007-5686-1
ISBN (Electronic)978-94-007-5687-8
DOIs
Publication statusPublished - 2013

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