Age-specific mortality among TB patients in Denmark 1998-2010

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Documents

  • Andreas Fløe
  • Anders Løkke
  • ,
  • Rikke Ibsen, i2minds, Aarhus, Danmark, Denmark
  • Ole Hilberg
Objective: To evaluate the age-specific mortality in a national TB cohort, and to estimate relative age-specific mortality compared with matched controls, in a retrospective case-control study.

Methods: Using Danish National Patient Registry, we retrospectively identified TB-patients between 1998-2010. They were matched to controls by age, gender, civil status and geography. Mortality data were obtained from Danish Civil Registration System. We calculated age-specific hazard ratio and cumulative survival function, adjusting for varying follow-up, distributing.

Results: 6713 cases and 28217 controls were followed for max. 12 (span: 0-12) years. Mortality was higher for cases than controls in all age groups, and significantly so for age groups above 20 years, peaking at a Hazard Ratio of 8.7 (95% CI: 5.53;16.69) in the 30-39 years age

Conclusion: Cumulative mortality of TB-patients is significantly inferior to matched controls. While the difference in survival is substantial among elderly patients, a high relative risk of dying is particularly of concern among young and middle-aged adult TB patients.
Original languageDanish
Publication year5 Sep 2015
Number of pages1
Publication statusPublished - 5 Sep 2015
EventEuropean Respiratory Society annual congress 2015 - RAI, Amsterdam, Netherlands
Duration: 5 Sep 20159 Sep 2015
Conference number: 25

Conference

ConferenceEuropean Respiratory Society annual congress 2015
Number25
LocationRAI
CountryNetherlands
CityAmsterdam
Period05/09/201509/09/2015

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