Advances in block copolymer-phospholipid hybrid vesicles: from physical-chemical properties to applications

Edit Brodszkij*, Brigitte Städler

*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

8 Citations (Scopus)

Abstract

Hybrid vesicles, made of lipids and amphiphilic block copolymers, have become increasingly popular thanks to their versatile properties that enable the construction of intricate membranes mimicking cellular structures. This tutorial review gives an overview over the different hybrid vesicle designs, and provides a detailed analysis of their properties, including their composition, membrane fluidity, membrane homogeneity, permeability, stability. The review puts emphasis on the application of these hybrid vesicles in bottom-up synthetic biology and aims to offer an overview of design guidelines, particularly focusing on composition, to eventually realize the intended applications of these hybrid vesicles.

Original languageEnglish
JournalChemical Science
Volume15
Issue28
Pages (from-to)10724-10744
Number of pages21
ISSN2041-6520
DOIs
Publication statusPublished - Jun 2024

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