Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Standard

Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate. / Tougaard, Rasmus Stilling; Søvsø Szocska Hansen, Esben; Laustsen, Christoffer; Lindhardt, Jakob; Schroeder, Marie; Bøtker, Hans Erik; Kim, Won Yong; Wiggers, Henrik; Stødkilde-Jørgensen, Hans.

2017. Abstract from ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State, Honolulu, United States.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Harvard

Tougaard, RS, Søvsø Szocska Hansen, E, Laustsen, C, Lindhardt, J, Schroeder, M, Bøtker, HE, Kim, WY, Wiggers, H & Stødkilde-Jørgensen, H 2017, 'Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate', ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State, Honolulu, United States, 22/04/2017 - 27/04/2017.

APA

Tougaard, R. S., Søvsø Szocska Hansen, E., Laustsen, C., Lindhardt, J., Schroeder, M., Bøtker, H. E., Kim, W. Y., Wiggers, H., & Stødkilde-Jørgensen, H. (2017). Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate. Abstract from ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State, Honolulu, United States.

CBE

Tougaard RS, Søvsø Szocska Hansen E, Laustsen C, Lindhardt J, Schroeder M, Bøtker HE, Kim WY, Wiggers H, Stødkilde-Jørgensen H. 2017. Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate. Abstract from ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State, Honolulu, United States.

MLA

Tougaard, Rasmus Stilling et al. Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate. ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State, 22 Apr 2017, Honolulu, United States, Conference abstract for conference, 2017.

Vancouver

Tougaard RS, Søvsø Szocska Hansen E, Laustsen C, Lindhardt J, Schroeder M, Bøtker HE et al. Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate. 2017. Abstract from ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State, Honolulu, United States.

Author

Bibtex

@conference{e0b39466412148be90e6b7980104351d,
title = "Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate",
abstract = "Deranged metabolism is now considered a key causal factor in heart failure and has therefore gained considerable scientific interest. The novel technique hyperpolarized MR has emerged as a leading methodological candidate to study these derangements. We employed a clinically relevant, large animal model of angiotensin-II-mediated acute hypertension to study cardiac metabolism in the setting of elevated afterload using hyperpolarized [1-13C]Pyruvate MR. The method was able to detect acute increases in both anaerobic and aerobic cardiac metabolism, which, in the future could mean a useful way of monitoring a possible treatment response to afterload reduction by using hyperpolarized MR.",
author = "Tougaard, {Rasmus Stilling} and {S{\o}vs{\o} Szocska Hansen}, Esben and Christoffer Laustsen and Jakob Lindhardt and Marie Schroeder and B{\o}tker, {Hans Erik} and Kim, {Won Yong} and Henrik Wiggers and Hans St{\o}dkilde-J{\o}rgensen",
year = "2017",
language = "English",
note = "ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State ; Conference date: 22-04-2017 Through 27-04-2017",

}

RIS

TY - ABST

T1 - Acute afterload-imposed change in porcine cardiac metabolism imaged by hyperpolarized [1-13C]Pyruvate

AU - Tougaard, Rasmus Stilling

AU - Søvsø Szocska Hansen, Esben

AU - Laustsen, Christoffer

AU - Lindhardt, Jakob

AU - Schroeder, Marie

AU - Bøtker, Hans Erik

AU - Kim, Won Yong

AU - Wiggers, Henrik

AU - Stødkilde-Jørgensen, Hans

PY - 2017

Y1 - 2017

N2 - Deranged metabolism is now considered a key causal factor in heart failure and has therefore gained considerable scientific interest. The novel technique hyperpolarized MR has emerged as a leading methodological candidate to study these derangements. We employed a clinically relevant, large animal model of angiotensin-II-mediated acute hypertension to study cardiac metabolism in the setting of elevated afterload using hyperpolarized [1-13C]Pyruvate MR. The method was able to detect acute increases in both anaerobic and aerobic cardiac metabolism, which, in the future could mean a useful way of monitoring a possible treatment response to afterload reduction by using hyperpolarized MR.

AB - Deranged metabolism is now considered a key causal factor in heart failure and has therefore gained considerable scientific interest. The novel technique hyperpolarized MR has emerged as a leading methodological candidate to study these derangements. We employed a clinically relevant, large animal model of angiotensin-II-mediated acute hypertension to study cardiac metabolism in the setting of elevated afterload using hyperpolarized [1-13C]Pyruvate MR. The method was able to detect acute increases in both anaerobic and aerobic cardiac metabolism, which, in the future could mean a useful way of monitoring a possible treatment response to afterload reduction by using hyperpolarized MR.

M3 - Conference abstract for conference

T2 - ISMRM 2017 Annual Meeting & Exhibition, Honolulu, United State

Y2 - 22 April 2017 through 27 April 2017

ER -