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Active Pumping in Endothelial Cell Tight Junctions

Research output: Contribution to conferencePosterResearch

Biomechanical factors have long been associated with the initiation and development of atherosclerosis. However, this research has primarily been focused on the importance of Wall Shear Stress (WSS), which has been shown to be low or oscillating in areas prone to the development of atherosclerotic plaques.1 The emergence of finite element solvers capable of coupling different physics has allowed further investigations into the initiation of atherosclerosis. In this abstract, we present a novel method for coupling mechanical deformations of endothelial cells to the mass transport of lipid through tight junctions.
Original languageEnglish
Publication yearMay 2011
Number of pages1
Publication statusPublished - May 2011
Externally publishedYes
EventBiomechanics in vascular Biology and Cardiovascular Disease - Rotterdam, Netherlands
Duration: 14 Apr 201115 Apr 2011


ConferenceBiomechanics in vascular Biology and Cardiovascular Disease

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ID: 38002797