ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection

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  • Shahab Nozohoor, Lunds Universitet
  • ,
  • Khalil Ahmad
  • Markus Bjurbom, Karolinska University Hospital, Stockholm
  • ,
  • Emma C. Hansson, University of Gothenburg
  • ,
  • Alexandra Heimisdottir, University of Gothenburg
  • ,
  • Anders Jeppsson, University of Gothenburg
  • ,
  • Ari Mennander, Heart Center, Tampere University Hospital, Tampere, Finland.
  • ,
  • Christian Olsson, Karolinska University Hospital, Stockholm
  • ,
  • Emily Pan, University of Turku
  • ,
  • Sigurdur Ragnarsson, Lunds Universitet
  • ,
  • Johan Sjögren, Lunds Universitet
  • ,
  • George Tellides, Yale School of Medicine
  • ,
  • Anders Wickbom, Örebro University
  • ,
  • Arnar Geirsson, Yale School of Medicine, Landspitali University Hospital
  • ,
  • Tomas Gudbjartsson, Landspitali University Hospital
  • ,
  • Igor Zindovic, Lunds Universitet

Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7–43.4)% vs 39.0 (95% CI 39.0–39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.

Original languageEnglish
JournalScandinavian Cardiovascular Journal
Volume54
Issue2
Pages (from-to)124-129
Number of pages6
ISSN1401-7431
DOIs
Publication statusPublished - 2020

    Research areas

  • aneurysm, Aorta, blood group, dissection, NORCAAD

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