A Systematic Review and Bayesian Meta-Analysis of Acoustic Measures of Prosody in Parkinson's Disease

TY - JOUR

T1 - A Systematic Review and Bayesian Meta-Analysis of Acoustic Measures of Prosody in Parkinson's Disease

AU - Fumel, Jules

AU - Bahuaud, Delphine

AU - Weed, Ethan

AU - Fusaroli, Riccardo

AU - Basirat, Anahita

PY - 2024/8/5

Y1 - 2024/8/5

N2 - Purpose: Linguistic prosody is affected in Parkinson’s disease (PD), which implicates the basal ganglia’s role in the production of prosody. However, there is no recent systematic synthesis of the available acoustic evidence of prosodic impairment in PD. This study aimed to identify the acoustic features of linguistic prosody that are consistently affected in PD. Method: The authors systematically reviewed articles that reported acoustic fea-tures of prosodic production in PD. Articles focused on fundamental frequency (F0) and its variability, intensity and its variability, speech and articulation rate, and pause duration and ratio. From a total of 648 records identified, 36 met cri-teria for inclusion and exclusion. For each acoustic measurement and task, data from people with PD (PwPD) were compared with those from controls to extract effect sizes. Pooled effect sizes were estimated using robust Bayesian hierarchi-cal regression models. Results: PD was associated with decreased F0 variability and increased pause duration. There was limited evidence of reduced intensity variability and speech rate in PwPD. No evidence was found to suggest that PD affects articulation rate or pause ratio. Conclusions: The primary acoustic parameters of prosody affected by PD are F0 variability and pause duration. The identification of these acoustic parame-ters has important clinical implications for the selection of PD management strategies. The association of F0 variability and pause duration with PD sug-gests that the neural circuits controlling these parameters are at least partly shared and might include the basal ganglia. While the current study focused on the phonetic realization of prosodic cues, future studies should examine whether and how PD affects prosody at higher levels of processing.

AB - Purpose: Linguistic prosody is affected in Parkinson’s disease (PD), which implicates the basal ganglia’s role in the production of prosody. However, there is no recent systematic synthesis of the available acoustic evidence of prosodic impairment in PD. This study aimed to identify the acoustic features of linguistic prosody that are consistently affected in PD. Method: The authors systematically reviewed articles that reported acoustic fea-tures of prosodic production in PD. Articles focused on fundamental frequency (F0) and its variability, intensity and its variability, speech and articulation rate, and pause duration and ratio. From a total of 648 records identified, 36 met cri-teria for inclusion and exclusion. For each acoustic measurement and task, data from people with PD (PwPD) were compared with those from controls to extract effect sizes. Pooled effect sizes were estimated using robust Bayesian hierarchi-cal regression models. Results: PD was associated with decreased F0 variability and increased pause duration. There was limited evidence of reduced intensity variability and speech rate in PwPD. No evidence was found to suggest that PD affects articulation rate or pause ratio. Conclusions: The primary acoustic parameters of prosody affected by PD are F0 variability and pause duration. The identification of these acoustic parame-ters has important clinical implications for the selection of PD management strategies. The association of F0 variability and pause duration with PD sug-gests that the neural circuits controlling these parameters are at least partly shared and might include the basal ganglia. While the current study focused on the phonetic realization of prosodic cues, future studies should examine whether and how PD affects prosody at higher levels of processing.

KW - Bayes Theorem

KW - Humans

KW - Parkinson Disease/physiopathology

KW - Speech Acoustics

KW - Speech Production Measurement/methods

UR - http://www.scopus.com/inward/record.url?scp=85200827013&partnerID=8YFLogxK

U2 - 10.1044/2024_JSLHR-23-00588

DO - 10.1044/2024_JSLHR-23-00588

M3 - Review

C2 - 39018262

SN - 1092-4388

VL - 67

SP - 2548

EP - 2564

JO - Journal of Speech, Language, and Hearing Research

JF - Journal of Speech, Language, and Hearing Research

IS - 8

ER -