A pilot study on the use of the super dimension navigation system for optimal cryobiopsy location in interstitial lung disease diagnostics

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A pilot study on the use of the super dimension navigation system for optimal cryobiopsy location in interstitial lung disease diagnostics. / Kronborg-White, S; Bendstrup, E; Gori, L et al.

In: Pulmonology, 12.09.2021.

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@article{cf98d08a6051431d95c53af30708538e,
title = "A pilot study on the use of the super dimension navigation system for optimal cryobiopsy location in interstitial lung disease diagnostics",
abstract = "BACKGROUND: Transbronchial cryobiopsies has become increasingly important in the diagnostic workup for interstitial lung diseases. The rate of complications and mortality are low compared to surgical lung biopsies, but the diagnostic yield is not as high. The reason for the lower diagnostic yield could in some cases be explained by biopsies taken too centrally or in less affected areas. In this pilot study we examined the feasibility of using the electromagnetic navigation system, superDimension (SD), when performing cryobiopsies to increase the diagnostic yield.METHODS: Electromagnetic navigation bronchoscopy and cryobiopsies were performed using SD. An electromagnetic board placed on the back of the patient and a position sensor at the tip of the navigational probe created a real-time 3D reconstruction of previously acquired computer tomography images. The procedure was performed with the patients in general anesthesia using a rigid bronchoscope when performed in Florence and with a flexible bronchoscope through an orotracheal tube when performed in Aarhus.RESULTS: In total, 18 patients were included. Five patients were excluded, partly due to technical difficulties. Disposable 1.7 mm cryoprobes were used in Aarhus, and reusable 1.9 mm probes in Florence. Pneumothorax was detected in three (23%), mild hemorrhage was seen in one (8%) and moderate hemorrhage in six (46%). The biopsies contributed to the diagnosis in 11 of the patients (85%).CONCLUSION: Using superDimension electromagnetic navigation system when performing cryobiopsies is feasible. A larger prospective trial is necessary to homogenize the technique between centres and to evaluate diagnostic advantage and complications.",
keywords = "Cryobiopsy, Electromagnetic navigation, Interstitial lung diseases, Interventional pulmonolgy, Super dimension",
author = "S Kronborg-White and E Bendstrup and L Gori and V Luzzi and Madsen, {L B} and V Poletti and Rasmussen, {T R} and M Trigiani and S Vezzosi and S Tomassetti",
note = "Copyright {\textcopyright} 2021 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espa{\~n}a, S.L.U. All rights reserved.",
year = "2021",
month = sep,
day = "12",
doi = "10.1016/j.pulmoe.2021.07.008",
language = "English",
journal = "Pulmonology",
issn = "2531-0429",
publisher = "Elsevier Espana",

}

RIS

TY - JOUR

T1 - A pilot study on the use of the super dimension navigation system for optimal cryobiopsy location in interstitial lung disease diagnostics

AU - Kronborg-White, S

AU - Bendstrup, E

AU - Gori, L

AU - Luzzi, V

AU - Madsen, L B

AU - Poletti, V

AU - Rasmussen, T R

AU - Trigiani, M

AU - Vezzosi, S

AU - Tomassetti, S

N1 - Copyright © 2021 Sociedade Portuguesa de Pneumologia. Published by Elsevier España, S.L.U. All rights reserved.

PY - 2021/9/12

Y1 - 2021/9/12

N2 - BACKGROUND: Transbronchial cryobiopsies has become increasingly important in the diagnostic workup for interstitial lung diseases. The rate of complications and mortality are low compared to surgical lung biopsies, but the diagnostic yield is not as high. The reason for the lower diagnostic yield could in some cases be explained by biopsies taken too centrally or in less affected areas. In this pilot study we examined the feasibility of using the electromagnetic navigation system, superDimension (SD), when performing cryobiopsies to increase the diagnostic yield.METHODS: Electromagnetic navigation bronchoscopy and cryobiopsies were performed using SD. An electromagnetic board placed on the back of the patient and a position sensor at the tip of the navigational probe created a real-time 3D reconstruction of previously acquired computer tomography images. The procedure was performed with the patients in general anesthesia using a rigid bronchoscope when performed in Florence and with a flexible bronchoscope through an orotracheal tube when performed in Aarhus.RESULTS: In total, 18 patients were included. Five patients were excluded, partly due to technical difficulties. Disposable 1.7 mm cryoprobes were used in Aarhus, and reusable 1.9 mm probes in Florence. Pneumothorax was detected in three (23%), mild hemorrhage was seen in one (8%) and moderate hemorrhage in six (46%). The biopsies contributed to the diagnosis in 11 of the patients (85%).CONCLUSION: Using superDimension electromagnetic navigation system when performing cryobiopsies is feasible. A larger prospective trial is necessary to homogenize the technique between centres and to evaluate diagnostic advantage and complications.

AB - BACKGROUND: Transbronchial cryobiopsies has become increasingly important in the diagnostic workup for interstitial lung diseases. The rate of complications and mortality are low compared to surgical lung biopsies, but the diagnostic yield is not as high. The reason for the lower diagnostic yield could in some cases be explained by biopsies taken too centrally or in less affected areas. In this pilot study we examined the feasibility of using the electromagnetic navigation system, superDimension (SD), when performing cryobiopsies to increase the diagnostic yield.METHODS: Electromagnetic navigation bronchoscopy and cryobiopsies were performed using SD. An electromagnetic board placed on the back of the patient and a position sensor at the tip of the navigational probe created a real-time 3D reconstruction of previously acquired computer tomography images. The procedure was performed with the patients in general anesthesia using a rigid bronchoscope when performed in Florence and with a flexible bronchoscope through an orotracheal tube when performed in Aarhus.RESULTS: In total, 18 patients were included. Five patients were excluded, partly due to technical difficulties. Disposable 1.7 mm cryoprobes were used in Aarhus, and reusable 1.9 mm probes in Florence. Pneumothorax was detected in three (23%), mild hemorrhage was seen in one (8%) and moderate hemorrhage in six (46%). The biopsies contributed to the diagnosis in 11 of the patients (85%).CONCLUSION: Using superDimension electromagnetic navigation system when performing cryobiopsies is feasible. A larger prospective trial is necessary to homogenize the technique between centres and to evaluate diagnostic advantage and complications.

KW - Cryobiopsy

KW - Electromagnetic navigation

KW - Interstitial lung diseases

KW - Interventional pulmonolgy

KW - Super dimension

U2 - 10.1016/j.pulmoe.2021.07.008

DO - 10.1016/j.pulmoe.2021.07.008

M3 - Journal article

C2 - 34526242

JO - Pulmonology

JF - Pulmonology

SN - 2531-0429

ER -