A novel nano-composite material for optically stimulated luminescence dosimetry

Camilla Lønborg Nielsen*, Rosana Martinez Turtos, Martin Bondesgaard, Jacob Søgaard Nyemann, Mads Lykke Jensen, Bo Brummerstedt Iversen, Ludvig Muren, Brian Julsgaard, Peter Balling

*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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Radiotherapy is a well-established and important treatment for cancer tumors, and advanced technologies can deliver doses in complex three-dimensional geometries tailored to each patient’s specific anatomy. A 3D dosimeter, based on optically stimulated luminescence (OSL), could provide a high accuracy and reusable tool for verifying such dose delivery. Nanoparticles of an OSL material embedded in a transparent matrix have previously been proposed as an inexpensive dosimeter, which can be read out using laser-based methods. Here, we show that Cu-doped LiF nanocubes (nano-LiF:Cu) are excellent candidates for 3D OSL dosimetry owing to their high sensitivity, dose linearity, and stability at ambient conditions. We demonstrate a scalable synthesis technique producing a material with the attractive properties of a single dosimetric trap and a single near-ultraviolet emission line well separated from visible-light stimulation sources. The observed transparency and light yield of silicone sheets with embedded nanocubes hold promise for future 3D OSL-based dosimetry.

Original languageEnglish
JournalNano Letters
Pages (from-to)1566-1572
Number of pages7
Publication statusPublished - Feb 2022


  • 3D Dosimetry
  • Flow Synthesis
  • Nanoparticles
  • Optically Stimulated Luminescence


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