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2015 Guidelines for Cardiopulmonary Resuscitation and Survival after Adult and Pediatric Out-of-Hospital Cardiac Arrest

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DOI

AIM: To evaluate whether the introduction of the 2015 Guidelines for CardiopulmonaryResuscitation were associated with a change in outcomes after out-of-hospital cardiac arrest (OHCA).

METHODS: Patients with OHCA were divided into adults (≥ 18 years) and pediatric cases (< 18 years). An interrupted time-series analysis was used to compare survival before (pre-guidelines January 1st, 2013 and October 31st, 2015) and after (post-guidelines May 1st, 2016 and December 31st, 2018) introduction of the 2015 guidelines. We fitted a regression model after dividing the time-period into segments with separate intercept and slope estimates.

RESULTS: We included 309,499 adults and 8,668 children with OHCA. There was no difference in the change in survival to hospital discharge with a favorable functional outcome per year between the two periods for adults (slope difference: -0.07% [95%CI -0.30 to 0.16], p = 0.55) and pediatric cases (slope difference: -0.01% [95%CI -1.35 to 1.32], p = 0.98). Likewise, we found no immediate change in survival to hospital discharge with a favorable functional outcome between the two periods for adults (0.20% (95%CI -0.21 to 0.61], p = 0.33) and pediatric cases (-1.08 [95%CI -3.44 to 1.27], p = 0.37).

CONCLUSION: Publication of the 2015 Guidelines for Cardiopulmonary Resuscitation was not associated with an increase in survival to hospital discharge with a favorable functional outcome after OHCA. Outcomes for OHCA have not improved the last 6 years in the United States.

Original languageEnglish
JournalEuropean Heart Journal - Quality of Care and Clinical Outcomes
Volume7
Issue4
Pages (from-to)407-415
Number of pages9
ISSN2058-1742
DOIs
Publication statusPublished - Oct 2021

    Research areas

  • Adults, Cardiopulmonary resuscitation, Guidelines, Out-of-hospital cardiac arrest, Paediatric

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