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11.74T fMRI of cortical and subcortical visual networks in the rat

Research output: Contribution to conferencePosterResearch

  • Christopher Bailey
  • Basavaraju G. Sanganahalli, MRRC, Yale University, New Haven, CT, USA, United States
  • Alyssa Siefert, Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA, United States
  • Herman Peter, MRRC, Yale University, New Haven, CT, USA, United States
  • Albert Gjedde, Denmark
  • Fahmeed Hyder, MRRC, Yale University, New Haven, CT, USA, United States
  • Center for Functionally Integrative Neuroscience
  • Positron Emission Tomography Center

Though a predominantly nocturnal animal, the rat has a functional visual system, albeit of low acuity, and has at least a basic form of color vision extending into the UV range. Our aim here was to develop methods to probe this system with both high field fMRI and electrophysiological techniques. Experimental setups in an imaging spectrometer are not ideally suited for studying the visual pathway of the rodent due to stringent physical constraints imposed by the imaging bore size and strong magnetic field. Here we report a method, applicable to both data acquisition scenarios, for specific and reproducible delivery of visual stimuli in fMRI as well as neurophysiology environments. It has the advantage of allowing variation of the stimulus source (e.g. colour of LED) without the need for manipulating the subject in the bore.

Original languageEnglish
Publication year2008
Publication statusPublished - 2008
Event16th ISMRM - Toronto, Canada
Duration: 3 May 20089 May 2008


Conference16th ISMRM

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ID: 11511720