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The effect of a novel Red Clover treatment on Menopausal symptoms and associated disorders

Project: Research

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The human menopause is associated with increased risk of osteoporosis, negative changes in lipid status, cardiovascular events, vasomotor symptoms and reduced quality of life. The aetiology of these effects is thought to derive from the deficiency and/or dysregulation of normal estrogen homeostasis caused by the menopause. Hormone replacement therapy has proved to be of limited use in this regard as there is general consensus that it increases cancer risk. Plant derived compounds that emulate the structure and behaviour of estrogen (known as phytoestrogens or isoflavones) have been of significant interest lately, as they may occupy the roles of estrogen without incurring negative effects associated with hormone replacement therapy. Red Clover is one plant species that is known be rich in isoflavones. Hence, extracts from this plant may potentially proffer preventative or therapeutic properties against menopause related risk factors.
The aim of this project is to determine whether a three month daily intake of a novel RC preparation can alleviate hot flush symptoms and associated disorders when compared with placebo.
Effective start/end date01/09/201101/11/2013


Research outputs

ID: 128987730