Research output per year
Research output per year
Project Details
Description
Project aim and background
There is an alarming rise in the frequency of metabolic syndrome (MeS), which increases the risk of cardiovascular disease (CVD) two-fold and type 2 diabetes (T2D) five-fold. Easy access to energy dense, unhealthy foods is a key factor responsible for this development. In this project we will study dietary strategies based on high protein and dietary fibre (DF) to mitigate MeS and the risk for CVD in human subjects fulfilling the criteria for MeS.
Project description
To obtain a more in-depth knowledge we will use an obese
porcine model, which allow more invasive exploration than in humans. In this model we will study the molecular consequences in adipose tissue and biofluids of development of obesity.
There is an alarming rise in the frequency of metabolic syndrome (MeS), which increases the risk of cardiovascular disease (CVD) two-fold and type 2 diabetes (T2D) five-fold. Easy access to energy dense, unhealthy foods is a key factor responsible for this development. In this project we will study dietary strategies based on high protein and dietary fibre (DF) to mitigate MeS and the risk for CVD in human subjects fulfilling the criteria for MeS.
Project description
To obtain a more in-depth knowledge we will use an obese
porcine model, which allow more invasive exploration than in humans. In this model we will study the molecular consequences in adipose tissue and biofluids of development of obesity.
| Acronym | MERITS |
|---|---|
| Status | Finished |
| Effective start/end date | 01/04/2015 → 30/06/2019 |
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Obesity development in a miniature Yucatan pig model – a multi-compartmental metabolomics study on cloned and normal pigs fed restricted or ad libitum high-energy diets
Curtasu, M. V., Knudsen, K. E. B., Callesen, H., Purup, S., Stagsted, J. & Hedemann, M. S., 2019, In: Journal of Proteome Research. 18, 1, p. 30-47 18 p.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Open AccessFile28 Citations (Scopus)273 Downloads (Pure) -
Ad libitum feeding alters several metabolic pathways in Yucatan minipigs - multi-compartmental metabolomics in animal obesity models
Curtasu, M. V., Knudsen, K. E. B., Callesen, H., Purup, S., Stagsted, J. & Hedemann, M. S., 2018.Research output: Contribution to conference › Poster › Research
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Development of diet induced obesity in female Göttingen minipigs is accompanied by increased population variance
Curtasu, M. V., Lærke, H. N., Knudsen, K. E. B. & Hedemann, M. S., 9 Nov 2017, p. 1. 1 p.Research output: Contribution to conference › Poster › Research
Activities
- 1 Lecture and oral contribution
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Ad libitum feeding alters several metabolic pathways in Yucatan minipigs - multi-compartmental metabolomics in animal obesity models
Curtasu, M. V. (Lecturer)
Aug 2018Activity: Presentations, memberships, employment, ownership and other activities › Lecture and oral contribution