In a balanced meal, meat contribute with proteins, fat, carbohydrates, vitamins, bioactive components, and minerals. However, traditional meat production is challenged, because it draws heavily on land and water resources and contribute significantly to greenhouse gas emission. Cultured meat is a future way to produce the same nutrients, with severely reduced impact on the environment. One of the largest challenges in culturing muscle cells in an economic sustainable way with consumer acceptance is eliminating fetal bovine serum (FBS) from the culture media. This project focuses on efficient modeling of culture media composition without FBS, by identifying and validating the combined effect of animal side-stream derived nutrients supplemented with recombinant growth factors for a cultured meat production in a circular perspective.