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Zexi Cai

Segregation of the structural variant responds for mastitis resistance in re-sequencing Nordic Holstein animals

Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

An important source of genome sequence variations, structural variants (SVs), are largely ignored due to the difficulty to precisely calling these variants. In this study, we used whole genome sequence (WGS) data to capture the SVs in various breeds. We have identified 84,561 SVs in 567 WGS animals. When compared the called SVs with the major quantitative trait locus for mastitis resistance on chromosome 6 near to GC gene, we found a duplication (DUP) is highly similar to previous reported copy number variant. Even though the linkage disequilibrium between the lead SNP for mastitis resistance and the called DUP is not complete, the SVs profile we obtained still showed the potential for identifying functional variants.
Original languageEnglish
Title of host publicationWCGALP 2022 Programme book
Number of pages4
PublisherWageningen Academic Publishers
Publication yearJul 2022
Publication statusPublished - Jul 2022
EventWorld Congress on Genetics Applied to Livestock Production - Rotterdam, Netherlands
Duration: 3 Jul 20228 Jul 2022
Conference number: 12


ConferenceWorld Congress on Genetics Applied to Livestock Production

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