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Zexi Cai

Organization, function and genetic controlling of synaptonemal complex

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • WJ Xie, Denmark
  • DY Shi, Denmark
  • ZX Cai
  • XY Chen
  • ,
  • WW Jin, Denmark
The synaptonemal complex (SC) is a super protein lattice that connects paired homologous chromosomes in most meiotic systems. This special organization is related to the meiosis processes such as homologous chromosomes pairing, synapsis, recombination, segregation, etc. Flaws of it would lead the meiocytes to apoptosis, which contributes to sterility. In recent years, the study of this complex has been a hotspot in meiosis research, but little was known about its exact mechanism. This review summarized the organization, function, and genetics of this complex with recent advances. Prospects of its further study we
re also briefly discussed.
Original languageUndefined/Unknown
JournalHereditas (Beijing)
Pages (from-to)167-176
Number of pages10
Publication statusPublished - 2012
Externally publishedYes

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