Vladimir Matchkov

Opto-mechanical microbridles for the determination of structural and functional properties of small resistance arteries

Research output: Contribution to book/anthology/report/proceedingArticle in proceedingsResearchpeer-review

  • Rosalia Rodriguez-Rodriguez, Universidad de Sevilla, Spain
  • Jose Antonio Plaza, Institut de Microelectrònica de Barcelona (IMB-CNM CSIC), Spain
  • Vladimir Matchkov
  • Ulf Simonsen
  • Maria Dolores Herrera, Universidad de Sevilla, Spain
  • Stephanus Buttgenbach, TU Braunschweig, Germany
  • Andreu Llobera, Institut de Microelectrònica de Barcelona (IMB-CNM CSIC)
  • ,
  • Xavier Munoz-Berbel, Institut de Microelectrònica de Barcelona (IMB-CNM CSIC), Spain

This work presents a polydimethylsiloxane (PDMS) system (named microbridle) monolithically integrating optical (microlenses, air mirrors etc.) and mechanical elements (cantilever) for the real time monitoring of dilatation and contraction events in small resistance arteries. Structural (response to intraluminal pressure changes) and functional properties (response to vasoactive substances) of mesenteric arteries were determined with the microbridle structure and compared to those obtained with conventional myograph systems. Both systems provide comparable data although microbridles were found advantageous in terms of precision, resolution (below the μm) and reliability for the poor contrast between sample and surrounding medium that impede reliable myography recordings.

Original languageEnglish
Title of host publicationMEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems
Number of pages4
PublisherInstitute of Electrical and Electronics Engineers Inc.
Publication year1 Jan 2014
Pages869-872
Article number6765779
ISBN (print)9781479935086
DOIs
Publication statusPublished - 1 Jan 2014
Event27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014 - San Francisco, CA, United States
Duration: 26 Jan 201430 Jan 2014

Conference

Conference27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014
LandUnited States
BySan Francisco, CA
Periode26/01/201430/01/2014
SponsorIEEE Robotics and Automation Society

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