Vladimir Matchkov

Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice

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Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice. / Boedtkjer, Ebbe; Prætorius, Jeppe; Matchkov, Vladimir V et al.

In: Circulation, Vol. 124, No. 17, 26.09.2011, p. 1819-1829.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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@article{d73a42c4587b4417bed55a1196bb2fc2,
title = "Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice",
abstract = "Disturbances in pH affect artery function, but the mechanistic background remains controversial. We investigated whether Na(+), HCO₃- transporter NBCn1, by regulating intracellular pH(pH₁), influences artery function and blood pressure regulation.",
keywords = "Animals, Calcium, Calcium Signaling, Endothelium, Vascular, Hypertension, Mesenteric Arteries, Mice, Mice, Inbred C57BL, Mice, Knockout, Muscle, Smooth, Vascular, Nitric Oxide, Organ Culture Techniques, Sodium-Bicarbonate Symporters, Sodium-Hydrogen Antiporter, Vasodilation",
author = "Ebbe Boedtkjer and Jeppe Pr{\ae}torius and Matchkov, {Vladimir V} and Edgaras Stankevicius and Susie Mogensen and F{\"u}chtbauer, {Annette C} and Ulf Simonsen and Ernst-Martin F{\"u}chtbauer and Christian Aalkjaer",
year = "2011",
month = sep,
day = "26",
doi = "10.1161/CIRCULATIONAHA.110.015974",
language = "English",
volume = "124",
pages = "1819--1829",
journal = "Circulation",
issn = "0009-7322",
publisher = "AHA/ASA",
number = "17",

}

RIS

TY - JOUR

T1 - Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice

AU - Boedtkjer, Ebbe

AU - Prætorius, Jeppe

AU - Matchkov, Vladimir V

AU - Stankevicius, Edgaras

AU - Mogensen, Susie

AU - Füchtbauer, Annette C

AU - Simonsen, Ulf

AU - Füchtbauer, Ernst-Martin

AU - Aalkjaer, Christian

PY - 2011/9/26

Y1 - 2011/9/26

N2 - Disturbances in pH affect artery function, but the mechanistic background remains controversial. We investigated whether Na(+), HCO₃- transporter NBCn1, by regulating intracellular pH(pH₁), influences artery function and blood pressure regulation.

AB - Disturbances in pH affect artery function, but the mechanistic background remains controversial. We investigated whether Na(+), HCO₃- transporter NBCn1, by regulating intracellular pH(pH₁), influences artery function and blood pressure regulation.

KW - Animals

KW - Calcium

KW - Calcium Signaling

KW - Endothelium, Vascular

KW - Hypertension

KW - Mesenteric Arteries

KW - Mice

KW - Mice, Inbred C57BL

KW - Mice, Knockout

KW - Muscle, Smooth, Vascular

KW - Nitric Oxide

KW - Organ Culture Techniques

KW - Sodium-Bicarbonate Symporters

KW - Sodium-Hydrogen Antiporter

KW - Vasodilation

U2 - 10.1161/CIRCULATIONAHA.110.015974

DO - 10.1161/CIRCULATIONAHA.110.015974

M3 - Journal article

C2 - 21947296

VL - 124

SP - 1819

EP - 1829

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 17

ER -