Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice. / Boedtkjer, Ebbe; Prætorius, Jeppe; Matchkov, Vladimir V et al.
In: Circulation, Vol. 124, No. 17, 26.09.2011, p. 1819-1829.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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TY - JOUR
T1 - Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice
AU - Boedtkjer, Ebbe
AU - Prætorius, Jeppe
AU - Matchkov, Vladimir V
AU - Stankevicius, Edgaras
AU - Mogensen, Susie
AU - Füchtbauer, Annette C
AU - Simonsen, Ulf
AU - Füchtbauer, Ernst-Martin
AU - Aalkjaer, Christian
PY - 2011/9/26
Y1 - 2011/9/26
N2 - Disturbances in pH affect artery function, but the mechanistic background remains controversial. We investigated whether Na(+), HCO₃- transporter NBCn1, by regulating intracellular pH(pH₁), influences artery function and blood pressure regulation.
AB - Disturbances in pH affect artery function, but the mechanistic background remains controversial. We investigated whether Na(+), HCO₃- transporter NBCn1, by regulating intracellular pH(pH₁), influences artery function and blood pressure regulation.
KW - Animals
KW - Calcium
KW - Calcium Signaling
KW - Endothelium, Vascular
KW - Hypertension
KW - Mesenteric Arteries
KW - Mice
KW - Mice, Inbred C57BL
KW - Mice, Knockout
KW - Muscle, Smooth, Vascular
KW - Nitric Oxide
KW - Organ Culture Techniques
KW - Sodium-Bicarbonate Symporters
KW - Sodium-Hydrogen Antiporter
KW - Vasodilation
U2 - 10.1161/CIRCULATIONAHA.110.015974
DO - 10.1161/CIRCULATIONAHA.110.015974
M3 - Journal article
C2 - 21947296
VL - 124
SP - 1819
EP - 1829
JO - Circulation
JF - Circulation
SN - 0009-7322
IS - 17
ER -